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个人简介
Jan Mol is principal investigator in the field of endocrinology, oncology and functional genomics of companion animals. He is project leader of the program on Comparative and Translational Oncology which is part of the Tissue Repair program of the faculty of Veterinary Medicine.
He is responsible for the scientific and laboratory part of the oncology program. The projects are focussed around the role of cancer stem cells in mammary gland, adrenal gland, and in insulinomas. The laboratory has ample expertise in gene expression studies (microarray, qRT-PCR), cell culture (transfection, organoid culture), FACS analysis and protein chemistry (IHC, Wblot).
His special interest is the role of progesterone in the pathogenesis of mammary cancer and in mammary cancer stem cell differentiation. Hallmarks are the discovery of the local mammary expression of growth hormone (GH) and IGF-I, expression analysis of mammary genes using microarray analysis, the unique role of the canine progesterone receptor-B and the Wnt signalling in mammary carcinogenesis.
研究兴趣
论文共 314 篇作者统计合作学者相似作者
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Felix van der Krift,Dick W. Zijlmans,Rhythm Shukla,Ali Javed,Panagiotis I. Koukos, Laura L.E. Schwarz,Elpetra P.M. Timmermans-Sprang,Peter E.M. Maas, Digvijay Gahtory, Maurits van den Nieuwboer,Jan A. Mol,Ger J. Strous,
Tugce Apaydin,Svetlana Zonis,Cuiqi Zhou, Christian Wong Valencia,Robert Barrett,Ger J. Strous,Jan A. Mol,Vera Chesnokova,Shlomo Melmed
ISCIENCEno. 11 (2023): 108117-108117
Lieke M. van der Velden, Peter Maas, Miranda van Amersfoort,Elpetra P. M. Timmermans-Sprang, Anneloes Mensinga, Elisabeth van der Vaart, Fabrice Malergue, Henk Vietor, Patrick W. B. Derksen,Judith Klumperman, Andreas van Agthoven, David A. Egan,
FRONTIERS IN ENDOCRINOLOGY (2022)
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