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个人简介
Research interests
Research in my group is focused on the basic biology of human pluripotent stem cells (hPSCs). HPSCs have the ability to self-renew indefinitely and to differentiate into any cell type. Thus, they hold great promise for the use in regenerative medicine and drug discovery. However, fulfilling the therapeutic and pharmaceutical potential of stem cells hinges on our ability to efficiently differentiate them towards a desired cell type. Furthermore, the cells must pose no safety risk upon transplantation into humans. This issue has been brought into focus by recognition that hPSCs acquire genetic changes upon prolonged culture, which mirror the changes found in human cancers. My group is researching the genetic stability of hPSCs, the extrinsic and intrinsic cues that govern the stem cell fates, and using hPSCs for disease modelling and drug discovery.
研究兴趣
论文共 14 篇作者统计合作学者相似作者
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Current protocolsno. 11 (2022)
biorxiv(2022)
Current protocolsno. 5 (2022)
biorxiv(2019)
International Journal of High Throughput Screening (2015): 1-13
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作者统计
#Papers: 28
#Citation: 167
H-Index: 7
G-Index: 12
Sociability: 5
Diversity: 1
Activity: 1
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