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Bio
Isamu Shiina is professor of chemistry at Tokyo University of Science (TUS), Japan.[1][2] He completed his BSc and MSc at TUS, and he joined the group of Prof. Teruaki Mukaiyama at TUS as an Assistant Professor in 1992. After receiving his PhD from the University of Tokyo (UT) in 1997, he was promoted to Lecturer at the TUS, and then appointed to an Associate Professor (2003) and a Full Professor (2008). He has received the Chemical Society of Japan (CSJ) Award for Young Chemists (1997), the CSJ Award for Creative Work (2013),[2][3] and the Commendation for Science and Technology Prizes by the Ministries of Japan (2015).[4] His research interests include the development of useful synthetic methods and the total synthesis of natural products.
Professor Isamu Shiina (Department of Applied Chemistry, Faculty of Science) was awarded the Prize for Science and Technology (Development Category) for "Development of the Dehydration Condensation Reactions for the Effective Syntheses of Pharmaceuticals and New Chemicals." He invented many methods for efficiently supplying biologically active molecules with complex structures, such as erythronolides, octalactins, and botcinins. The basic strategy is one wherein chain compounds are constructed through a stereoselective aldol reaction, and end parts of which are linked via a cyclization reaction. In particular, the dehydration condensation reaction using 2-methyl-6-nitrobenzoic anhydride (MNBA), which he developed in recent years, is suitable for synthesis of unstable molecules and is now being widely used around the globe in fields such as pharmaceutical production.
Research Interests
Papers共 312 篇Author StatisticsCo-AuthorSimilar Experts
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Miyuki Natsume,Mariko Niwa, Sho Ichikawa, Takuma Okamoto,Hisazumi Tsutsui, Daiki Usukura,Takatsugu Murata,Ryo Abe,Motoyuki Shimonaka,Toshirou Nishida,Isamu Shiina,Yuuki Obata
Isamu Shiina,Takashi Iizumi, Saori Taniguchi,Masuhiro Sugimoto,Takahisa Shimazaki,Yu-suke Yamai, Go Ogawa, Tetsuro Yamada,Shojiro Shinohara, Yosuke Kageyama,Teppei Kuboki, Yuki Suwa,
Organic lettersno. 16 (2024): 3327-3331
Takatsugu Murata, Takuto Iwayama,Teppei Kuboki, Shotaro Taguchi, Shou Tsugawa,Takumi Yoshida,Hisazumi Tsutsui, Ayana Shimauchi, Yukiho Kosaka,Isamu Shiina
crossref(2023)
ACS omegano. 33 (2023): 30789-30789
crossref(2023)
Isamu Shiina,Takashi Iizumi, Saori Taniguchi, Masuhiro Sugimoto,Takahisa Shimazaki, Yu-suke Yamai, Go Ogawa, Tetsuro Yamada, Shojiro Shinohara, Yosuke Kageyama, Teppei Kuboki, Yuki Suwa,
ORGANIC LETTERSno. 16 (2023): 3327-3331
crossref(2023)
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Author Statistics
#Papers: 323
#Citation: 8181
H-Index: 45
G-Index: 77
Sociability: 6
Diversity: 1
Activity: 1
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