Inderjeet Dokal’s principal research interest is the pathophysiology of aplastic anaemia (AA)/bone mar-row failure. In order to understand the biology of aplastic anaemia he has focused on monogenic dis-orders associated with AA. As a MRC Research Fellow he was able to delineate some of the cellular features of two of the commonest inherited bone marrow failure syndromes, Fanconi anaemia (FA) and dyskeratosis congenita (DC). Subsequently, in order to facilitate research on DC and related dis-orders he established an international bone marrow failure registry in 1995 and a close collaboration with Philip Mason and Tom Vulliamy. In addition to providing a genetic resource the registry has enabled the documentation of clinical, haematological and other features of patients with bone marrow failure syndromes and a more co-ordinated clinical management.