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个人简介
Dr. Ilan Tsarfaty received his BSc. (1983), MSc. (1986) and Ph.D. (1990) from Tel Aviv University. From 1991-1994, he served as a postdoctoral research associate at the National Cancer Institute's Frederick Cancer Research and Development Center. He was a visiting scientist at the Van Andel Research Institute Grand Rapids MI as a part of the Molecular Imaging Center University of Michigan (2001 - 2003). Dr. Tsarfaty has been a member of the Department of Clinical Microbiology and Immunology, Sackler School of Medicine, Tel Aviv University since 1994. He is the author of over 65 scientific research articles and over ten book chapters. Dr. Tsarfaty cloned the gene of the breast cancer antigen Muc1 and showed its potential use as a marker for breast cancer. He was the first to show that the Met tyrosine kinase growth factor receptor is involved in tubule formation in mammary tubule and in mesenchymal-epithelial cell conversion.
Dr. Tsarfaty was the first to show that Met is a prognostic factor for breast cancer patients. He also demonstrated that HGF/SF alters metabolic activity by induction of Mimp, a novel gene that is involved in metastasis that was cloned and characterized in Dr. Tsarfaty's lab. Dr. Tsarfaty has been leading an effort to develop noninvasive breast tumor molecular imaging modalities as a powerful tool in understanding the metabolic activity induced by Met signal transduction. This technology enhances the definition of tumor margins and may allow earlier detection of smaller tumors and small metastatic lesions. Currently, Dr. Tsarfaty's lab is in the process of understanding the physical, cellular, and molecular mechanisms of Met induced motility leading to embryo development and metastasis.
研究兴趣
论文共 118 篇作者统计合作学者相似作者
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Shmuel Avlas, Hala Kassis,Michal Itan,Hadar Reichman,Avishay Dolitzky, Inbal Hazut,Sharon Grisaru-Tal,Yaara Gordon,Ilan Tsarfaty, Danielle Karo-Atar,Perri Rozenberg,Almog Bitton,
Frontiers in immunology (2023): 1050245-1050245
Chao-Nan Qian,Bree Berghuis,Galia Tsarfaty, MaryBeth Bruch,Eric J. Kort, Jon Ditlev,Ilan Tsarfaty,Eric Hudson, David G. Jackson,David Petillo,Jindong Chen,James H. Resau,
crossref(2023)
Oncotargetno. 1 (2023): 366-376
Chao-Nan Qian,Bree Berghuis,Galia Tsarfaty, MaryBeth Bruch,Eric J. Kort, Jon Ditlev,Ilan Tsarfaty, Eric Hudson, David G. Jackson,David Petillo,Jindong Chen,James H. Resau,
crossref(2023)
Chao-Nan Qian,Bree Berghuis,Galia Tsarfaty, MaryBeth Bruch,Eric J. Kort, Jon Ditlev,Ilan Tsarfaty,Eric Hudson, David G. Jackson,David Petillo,Jindong Chen,James H. Resau,
crossref(2023)
Chao-Nan Qian,Bree Berghuis,Galia Tsarfaty, MaryBeth Bruch,Eric J. Kort, Jon Ditlev,Ilan Tsarfaty,Eric Hudson, David G. Jackson,David Petillo,Jindong Chen,James H. Resau,
crossref(2023)
Clinical Cancer Researchno. 5 (2021)
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