Iain A M Macphee

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Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses of AZD2373, an Antisense Oligonucleotide Targeting APOL1

Peter J. Greasley, Nikhil Agrawal,Magnus Althage,Jose Sanchez,Sarah Kirk,Erlend Johannessen Egeland,Magnus Astrand, Helena Westergren, James Sherwood, Michael Mccarthy,Uptal Patel,Iain Macphee

NEPHROLOGY DIALYSIS TRANSPLANTATION (2024): I1134-I1135

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A Drug-Drug Interaction Study and Physiologically Based Pharmacokinetic Modelling to Assess the Effect of an Oral 5-Lipoxygenase Activating Protein Inhibitor on the Pharmacokinetics of Oral Midazolam

Jane Knochel,Vijender Panduga,Karin Nelander,Maria Heijer,Eva-Lotte Lindstedt, Hodan Ali,Malin Aurell, Helena Odesjo,Pablo Forte, Kat Connolly,Hans Ericsson,Iain Macphee

British Journal of Clinical Pharmacology (2024)

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#1003 Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses of AZD2373, an Antisense Oligonucleotide Targeting APOL1

Peter J Greasley, Nikhil Agrawal,Magnus Althage,Jose Sanchez,Sarah Kirk,Erlend Johannessen Egeland,Magnus Åstrand, Helena Westergren, James Sherwood, Michael Mccarthy,Uptal Patel,Iain Macphee

Nephrology Dialysis Transplantationno. Supplement_1 (2024)

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A Phase IIb Randomized, Double-Blind, Placebo-Controlled, Multi-Centre, Dose Ranging Study of Atuliflapon in Participants with Proteinuric CKD

Hiddo J. Heerspink, Marcin Ufnal,C Gordon Law,Carl A. Whatling,Hans I. Ericsson,Jane Knöchel, Kathleen Connolly, Russell J. Kinch,Iain MacPhee

Journal of the American Society of Nephrologyno. 11S (2023): 677-678

引用2浏览0引用

Limited Sampling Strategies for Estimation of Tacrolimus Exposure in Kidney Transplant Recipients Receiving Extended‐release Tacrolimus Preparation

Toqa El-Nahhas,Joyce Popoola,Iain MacPhee,Atholl Johnston

CTS-CLINICAL AND TRANSLATIONAL SCIENCE（2022）

引用6浏览0WOS引用

Investigating Lysozyme As a Mediator of Tubular Epithelial Inflammation: an Example of CKD Knowledge Graph Target Discovery and Validation

Kevin Woollard,Barbara Musial, Karolina A. Nilsson,Elena Liarte Marin,Lisa Buvall,Iain MacPhee,Maria Ryaboshapkina,Ufuk Kirik,Dirk S. Paul,Mohammad Bohlooly,Andrea Taddei, Delphine M. Rolando, Andres Mori,Claus Bendtsen,Pernille B. Laerkegaard Hansen

Journal of the American Society of Nephrologyno. 11S (2022): 601-601

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Design of FLAIR: a Phase 2b Study of the 5-Lipoxygenase Activating Protein Inhibitor AZD5718 in Patients with Proteinuric CKD

Hiddo J. L. Heerspink,Gordon Law,Konstantina Psachoulia, Kathleen Connolly,Carl Whatling,Hans Ericsson,Jane Knochel,Eva-Lotte Lindstedt,Iain MacPhee

Kidney international reports（2021）

引用10浏览0WOS引用

Urine APOL1 Isoforms Reflect Plasma-Derived Liver-Synthesized Proteins

Magnus Althage,Timothy M. Heinrich,Tasso Miliotis,Anna Bogstedt,Lijun Ma,Michael D. Gautreaux,Pamela J. Hicks,Nicholette D. Palmer,Iain MacPhee,Judith Hartleib-Geschwindner,Peter J. Greasley,Barry I. Freedman

Journal of the American Society of Nephrology JASN（2021）

引用1浏览0WOS引用

Integrin aVb8/TGF-b Activation in Kidney Is Associated with Renal Function Deterioration and Can Be Monitored in Urine

Xiaozhen Wang,James Conway, Kristina Kovacina,Stephanie C. Heasman,Elena Liarte Marin,Sonja Hess,Chelsea Boo,Denis Feliers,David J. Baker,Marvin V. Sinsakul,Iain MacPhee,Viknesh Selvarajah,Sven M. Moosmang,Judith Hsia,Judith Hartleib-Geschwindner

Journal of the American Society of Nephrologyno. 10S (2020): 316-317

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Artificial Intelligence-Driven Target Identification in CKD

Chanchal Kumar,Lisa Buvall,Maria Ryaboshapkina,Kevin Woollard,Julie Williams, Natalie Kurbatova,Anna Reznichenko,Iain MacPhee,Mohammad Bohlooly,Dirk S. Paul,James Dunbar,Andrea Taddei,Mark Davies, Siobhan McMahon, Andres Mori,Regina Fritsche-Danielson,Claus Bendtsen,Pernille B. Laerkegaard Hansen

Journal of the American Society of Nephrologyno. 10S (2020): 247-247

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论文共 198 篇作者统计合作学者相似作者