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Dr. Pack is pursuing research on genetics/genomics of sleep and its disorders. His laboratory is conducting studies in Drosophila and mice and translating these findings to humans. A particular focus of Dr. Pack’s work is to evaluate the genetic determinants of sleep homeostasis. Studies are ongoing to evaluate molecular mechanisms of sleepiness and sleep promotion using both hypothesis-driven and discovery science. The latter involves analysis of the changes in the transcription with sleep/wake and sleep deprivation in identified neuronal populations. Techniques being used include behavioral/sleep studies in Drosophila and mice, RT-PCR, Western analysis of protein, expression profiling, laser microcapture dissection, RNA seq and immunohistochemistry. Dr. Pack is committed to research training and directs three training grants from the National Institutes of Health.
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Albrecht P. A. Vorster, Eus J. W. van Someren,Allan I. Pack,Reto Huber,Markus H. Schmidt,Claudio L. A. Bassetti
CLINICAL AND TRANSLATIONAL NEUROSCIENCEno. 1 (2024)
Sleep and Breathingpp.1-13, (2024)
Cell Reportsno. 5 (2024): 114192-114192
Annals of the American Thoracic Societyno. 6 (2023): 880-890
Science Advancesno. 1 (2023)
CoRR (2023)
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Jolie L. Chang,Andrew N. Goldberg,Jeremiah A. Alt, Alzoubaidi Mohammed, Liza Ashbrook,Dennis Auckley,Indu Ayappa, Hira Bakhtiar,Jose E. Barrera,Bethany L. Bartley,Martha E. Billings,Maurits S. Boon,
ERJ open researchno. 2 (2023): 00443-2022
The American journal of managed careno. 5 (2023): 256-263
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