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Career Trajectory
Bio
PhD. Iratxe Madarieta (female) obtained her degree in Biological Sciences in 1999 and her PhD in chemistry in 2012 by the University of the Basque Country. She is senior researcher in the Biomaterials Area-Health Division of TECNALIA with more than 20 years of experience in the research of Biomaterials. Initially, she was focused on the biocompatibility studies and on the development of advanced therapeutic and regenerative biomaterials in 2D and 3D in vitro cellular models. During this period, she achieved a new therapeutic material for a corneal implant as an inventor of a patent ("Implantable optical system, method for developing it and applications" WO2008020087). In the last 10 years she has focused her research on the investigation and development of biologic scaffold materials, particularly on adipose tissue-derived extracellular matrices. She developed a simple and specific method to decellularize adipose tissue and have led her to obtain a product by process patent ("Method for producing a decellularized tissue matrix" WO2016EP82849). She is currently focusing her research on the application of several extracellular matrix-derived biomaterials in tissue engineering and regenerative medicine. Concretely, she investigates the stem (dental pump, adipose, neuronal) and primary (dermal fibroblast, neural, adipocytes, myoblasts) cell behavior when are cultured in extracellular matrix-derived materials processed by numerous technologies, such as, in situ polymerizable hydrogels for cell encapsulation and therapy, 3D bioprinting of tissue models, solid foams and coatings incorporated in innovative microplates for in vitro normal and disease 2D and 3D tissue models. These investigations achieved more than 4 publications in the las two years, showing the excellent processability and biologic activity of the adipose-derived extracellular matrix material obtained by the invented decellularized methodology. Investigations had led to observe an intrinsic capacity of the decellularized adipose matrix for osteogenic and adipogenic differentiation of mesenchymal stem cells and an enhanced adhesion and viability of a wide range of cells. Once these results could be validated, new products might be commercialized for in vitro microtissue models, organ-on-a-chip devices, electrophysiology, and regenerative medicine.
Research Interests
Papers共 14 篇Author StatisticsCo-AuthorSimilar Experts
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BIOMATERIALS ADVANCES (2024): 213794-213794
Jon Luzuriaga,Nerea Garcia-Urkia, Jone Salvador-Moya,Beatriz Pardo-Rodriguez, Iker Etxebarria,Francisco-Javier Fernandez-San-Argimiro,Beatriz Olalde,Fernando Unda,Jose Ramon Pineda,Iratxe Madarieta,Gaskon Ibarretxe
EUROPEAN CELLS & MATERIALS (2023): 119-137
CHEMICAL ENGINEERING JOURNAL (2023): 144980
Biomaterials advances (2023): 213351-213351
BIOLOGY-BASELno. 8 (2022): 1099-1099
Cristina Del Amo, Xabier Fernandez-San Argimiro, Maria Cascajo-Castresana,Arantza Perez-Valle,Iratxe Madarieta,Beatriz Olalde,Isabel Andia
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Author Statistics
#Papers: 13
#Citation: 58
H-Index: 4
G-Index: 7
Sociability: 4
Diversity: 2
Activity: 14
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