基本信息
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Career Trajectory
Bio
Dr. Husseini K. Manji is the Global Therapeutic Head for Neuroscience at Janssen Research &
Development, LLC, one of the Janssen Pharmaceutical Companies of Johnson & Johnson. He was
previously Chief, Laboratory of Molecular Pathophysiology & Experimental Therapeutics, NIH, and
director of the NIH Mood and Anxiety Disorders Program, the largest program of its kind in the world.
He is also a visiting professor at Duke University.
Dr. Manji received his B.S. (Biochemistry) and M.D. from the University of British Columbia. Following
residency training, he completed fellowship training at the NIMH and obtained extensive additional
training in cellular and molecular biology at the NIDDK. The major focus of his research has been the
investigation of disease- and treatment-induced changes in gene and protein networks that regulate
synaptic and neural plasticity in neuropsychiatric disorders. His work has helped to conceptualize these
illnesses as genetically-influenced disorders of synaptic and neural plasticity, and has led to the
investigation of novel therapeutics for refractory patients. He has also been actively involved in the
development of biomarkers to help refine these multifactoral diseases into mechanism-based
subcategories to develop targeted therapeutics.
Research Interests
Papers共 256 篇Author StatisticsCo-AuthorSimilar Experts
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Ochs-Ross Rachel,Wajs Ewa,J Daly Ella, Zhang Yun,Lane Rosanne, Lim Pilar,Hough David,Manji Husseini,C Drevets Wayne, C Steffens David, B Singh Jaskaran
American Journal of Geriatric Psychiatry (2021): 127-128
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Nature Reviews Drug Discoveryno. 6 (2020): 427-427
Ewa Wajs,Leah Aluisio, Richard Holder,Ella J Daly,Rosanne Lane,Pilar Lim, Joyce E George,Randall L Morrison,Gerard Sanacora,Allan H Young,Siegfried Kasper,Ahmad Hatim Sulaiman,
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