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Current research in the group of Hubert Hilbi focuses on the topics „Virulence and communication of Legionella“. Recent projects comprise (i) the characterization of novel translocated Legionella effectors that anchor to host phosphoinositide lipids, activate small GTPases, inhibit the retromer complex or degrade the chelator phytate, (ii) the role of host factors implicated in retrograde trafficking (retromer, OCRL) or ER dynamics (atlastin) during intracellular replication, (iii) the purification and proteomics of intact “Legionella-containing vacuoles” from infected phagocytes, and (iv) the analysis of the Legionella quorum sensing (Lqs) system and the cognate α-hydroxyketone signaling molecule LAI-1. Moreover, the group of Hubert Hilbi is also engaged in research on Mycobacterium marinum and the interactions of this pathogen with eukaryotic host cells.
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论文共 182 篇作者统计合作学者相似作者
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Molecular microbiologyno. 2 (2023): 194-209
Methods in molecular biology (Clifton, N.J.) (2023): 63-85
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2023)
Aby Anand, Anna-Carina Mazur, Patricia Rosell-Arevalo,Rico Franzkoch,Leonhard Breitsprecher, Stevanus A. Listian, Sylvana V. Hüttel, Danica Müller, Deise G. Schäfer,Simone Vormittag,Hubert Hilbi,Markus Maniak,
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature (2023)
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bioRxiv (Cold Spring Harbor Laboratory)no. 12 (2023): 105376-105376
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