基本信息
views: 4
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
My long-term research interest is to improve delivery of Morpholinos into cells in adult tissues, enabling the therapeutic use of Morpholinos for treatment of a broad range of diseases. Chemical structures have been found which, when linked to a Morpholino oligo, enhance the delivery of the Morpholinos from blood into the cytosol of cells. I invented a class of compounds, the peptide-linked Morpholino oligos (PPMO), which are in clinical trials and are the workhorse molecules produced in my laboratory for many applications for eukaryotic and prokaryotic systems. I am also studying alternative strategies for enhancing Morpholino delivery in vivo by other chemical modifications and formulations.
Research Interests
Papers共 118 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Miriam Ruth Heindl, Anna-Lena Rupp,Marie Schwerdtner, Dorothea Bestle, Anne Harbig, Amy De Rocher,Luna C. Schmacke, Bart Staker,Torsten Steinmetzer, David A. Stein,Hong M. Moulton,Eva Boettcher-Friebertshaeuser
Cell‐Penetrating Peptidespp.263-284, (2022)
Social Science Research Network (2022)
Kenji Rowel Q. Lim,Stanley Woo, Dyanna Melo, Yiqing Huang, Kasia Dzierlega, Md Nur Ahad Shah, Tejal Aslesh,Rohini Roy Roshmi,Yusuke Echigoya,Rika Maruyama,Hong M. Moulton,Toshifumi Yokota
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPYno. 2 (2021): 413-417
Dorothea Bestle,Hannah Limburg, Diana Kruhl,Anne Harbig,David A. Stein,Hong Moulton,Mikhail Matrosovich,Elsayed M. Abdelwhab,Juergen Stech, Eva Boettcher-Friebertshaeuser
Load More
Author Statistics
#Papers: 112
#Citation: 7353
H-Index: 45
G-Index: 85
Sociability: 6
Diversity: 3
Activity: 38
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn