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本课题组聚焦于肿瘤免疫逃逸机制研究及基于新靶点、新机制的小分子肿瘤免疫治疗药物的发现。研究内容主要包括:1、PD-L1等肿瘤免疫检查点蛋白分子调控机制的研究,发现药物作用新靶点,研发小分子肿瘤免疫治疗药物。2、天然活性药物干预肿瘤微环境中TAM、MDSC等重塑免疫监控的研究等。
Research Interests
Papers共 20 篇Author StatisticsCo-AuthorSimilar Experts
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ACTA PHARMACEUTICA SINICA Bno. 3 (2024)
Yulong Shi, Fenbei Chen,Mengyuan Wu,Xin Zhang, Runze Meng,Kun Wang,Yan Wang,Yuheng Mei,Qionglu Duan,Yinghong Li,Rongmei Gao,Yuhuan Li,
CHINESE CHEMICAL LETTERSno. 5 (2024): 108792-108792
FRONTIERS IN PHARMACOLOGY (2023): 1251731-1251731
Scientific reportsno. 1 (2017): 41862-41862
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