基本信息
浏览量:189
职业迁徙
个人简介
Dr. Lin’s work is focused on the self-renewing mechanism of stem cells, using Drosophila germline stem cells, mouse germline stem cells, mouse embryonic stem cells, Hydra, and planarian stem cells as models. He also studies germline development and stem cell-related cancers.
Dr. Lin has made key contributions to the demonstration of stem cell asymmetric division and the proof of the stem cell niche theory. He discovered the Argonaute/Piwi gene family and elucidated their essential function in stem cell self-renewal and germline development. He is also a discoverer of a novel class of non-coding small RNAs called PIWI-interacting RNAs (piRNAs), a discovery hailed by the Science Magazine as one of the Ten Scientific Breakthroughs in 2006. More recently, he proposed and demonstrated the crucial roles of the Piwi-piRNA pathway in epigenetic programming of gene expression and in post-transcriptional regulation of mRNAs and lncRNAs.
Dr. Lin received many awards and honors, including the Jane Coffin Childs Fellowship for Medical Research (1990), American Cancer Society Junior Faculty Research Award (1996), the March of Dimes Basil O'Connor Scholar Research Award (1996), the David and Lucile Packard Fellowship for Science and Engineering (1996), the G. Harold and Leila Y. Mathers Award (2007, 2011, 2015), the American Society of Andrology Lecturer Award (2008), the Laura Hartenbaum Breast Cancer Foundation’s Legacy for Hope Award (2009), the Ellison Medical Foundation Senior Scholar Award (2010), the NIH Director’s Pioneer Award (2010), the NIH MERIT Award (2012), the Ray Wu Award (the highest honor by the Chinese Biological Investigators Society; 2013), and the Society for the Study of Reproduction Research Award (2015), and the Chinese Association for Science and Technology, USA, Outstanding Science and Innovation Award (2019). He is a Member of US National Academy of Sciences (2018-), a Member of American academy of Arts and Sciences (2018-), and a Fellow of the American Association for the Advancement of Science (2010-).
Dr. Lin has made key contributions to the demonstration of stem cell asymmetric division and the proof of the stem cell niche theory. He discovered the Argonaute/Piwi gene family and elucidated their essential function in stem cell self-renewal and germline development. He is also a discoverer of a novel class of non-coding small RNAs called PIWI-interacting RNAs (piRNAs), a discovery hailed by the Science Magazine as one of the Ten Scientific Breakthroughs in 2006. More recently, he proposed and demonstrated the crucial roles of the Piwi-piRNA pathway in epigenetic programming of gene expression and in post-transcriptional regulation of mRNAs and lncRNAs.
Dr. Lin received many awards and honors, including the Jane Coffin Childs Fellowship for Medical Research (1990), American Cancer Society Junior Faculty Research Award (1996), the March of Dimes Basil O'Connor Scholar Research Award (1996), the David and Lucile Packard Fellowship for Science and Engineering (1996), the G. Harold and Leila Y. Mathers Award (2007, 2011, 2015), the American Society of Andrology Lecturer Award (2008), the Laura Hartenbaum Breast Cancer Foundation’s Legacy for Hope Award (2009), the Ellison Medical Foundation Senior Scholar Award (2010), the NIH Director’s Pioneer Award (2010), the NIH MERIT Award (2012), the Ray Wu Award (the highest honor by the Chinese Biological Investigators Society; 2013), and the Society for the Study of Reproduction Research Award (2015), and the Chinese Association for Science and Technology, USA, Outstanding Science and Innovation Award (2019). He is a Member of US National Academy of Sciences (2018-), a Member of American academy of Arts and Sciences (2018-), and a Fellow of the American Association for the Advancement of Science (2010-).
研究兴趣
论文共 173 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Molecular Cellno. 8 (2024): 1475-1495.e18
Prajwal Boddu,Abhishek Gupta, Rahul Roy,barbara De La Pena Avalos, Anne Olazabal Herrero,Joshua Zimmer,Matthew Simon,Namrata Sonia Chandhok, Darren King,Nils Neuenkirchen, Elois Dray,Haifan Lin,
Blood (2023): 714
Prajwal C Boddu,Abhishek K Gupta,Rahul Roy,Barbara De La Pena Avalos, Ane Olazabal Herrero,Nils Neuenkirchen,Joshua Zimmer,Namrata S Chandhok,Darren King, Yashuhito Nannya,Seishi Ogawa,Haifan Lin,
biorxiv(2023)
Phan Q. Duy, Stefan C. Weise, Claudia Marini,Xiao-Jun Li,Dan Liang,Peter J. Dahl,Shaojie Ma,Ana Spajic,Weilai Dong,Jane Juusola,Emre Kiziltug,Adam J. Kundishora,
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn