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In development a single cell goes through a series of repeated divisions and these cells read the program encoded in their DNA in order to become familiar cell types such as those found in muscle, liver or our brains. The goal of our lab is to uncover the rules behind these decisions with the objective of predicting and manipulating developmental programs from just looking at DNA sequence. In order to reach this predictive understanding we combine physics, synthetic biology and new technologies to query and control developmental decisions in real time at the single cell level in the fruit fly embryo.
In development a single cell goes through a series of repeated divisions and these cells read the program encoded in their DNA in order to become familiar cell types such as those found in muscle, liver or our brains. The goal of our lab is to uncover the rules behind these decisions with the objective of predicting and manipulating developmental programs from just looking at DNA sequence. In order to reach this predictive understanding we combine physics, synthetic biology and new technologies to query and control developmental decisions in real time at the single cell level in the fruit fly embryo.
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论文共 138 篇作者统计合作学者相似作者
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bioRxiv : the preprint server for biology (2024)
ArXiv (2024)
Results in Engineering (2024): 102546
bioRxiv : the preprint server for biology (2024)
Elizabeth Eck,Bruno Moretti, Brandon H. Schlomann,Jordão Bragantini,Merlin Lange, Xiang Zhao,Shruthi VijayKumar,Guillaume Valentin, Cristina Loureiro,Daniele Soroldoni,Loïc A. Royer,Andrew C. Oates,
bioRxiv the preprint server for biology (2024)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Proceedings of the National Academy of Sciencesno. 10 (2023): e2211203120-e2211203120
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