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Autologous adult human skeletal muscle cells have numerous potential cell transplantation applications, including regenerating heart and skeletal muscle, and for therapeutic protein delivery when genetically engineered to express a recombinant protein. Our research examines the survival and functionality of human muscle cells transplanted in vivo for the development of improved methods for the treatment of numerous endocrine, neuromuscular, and cardiovascular disorders.
Autologous adult human skeletal muscle cells have numerous potential cell transplantation applications, including regenerating heart and skeletal muscle, and for therapeutic protein delivery when genetically engineered to express a recombinant protein. Our research examines the survival and functionality of human muscle cells transplanted in vivo for the development of improved methods for the treatment of numerous endocrine, neuromuscular, and cardiovascular disorders.
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Science Translational Medicineno. 614 (2021): eabe8868-eabe8868
Nature Biotechnologyno. 3 (2019): 215-216
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