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Oncologist Henry S. Kaplan made major contributions to our understanding of cancer and to its treatment. He was a pioneer in the advancement of radiation therapy as a treatment for some cancers. Along with colleague Edward Ginzton, Kaplan adapted the electron linear accelerator (typically used by atomic physicists at the time) so it could be used for medical use. This invention made it possible to precisely direct radiation at the diseased area in order to prevent any permanent damage to other surrounding organs (which drastically reduced the possibility of sterility from radio therapy). By combining chemotherapy and his innovative radiation therapy, Kaplan made Hodgkin’s disease, a previously untreatable cancer that attacked the lymphatic system, one of the most curable forms of cancer. Despite the significance of this oncological breakthrough, his most important discovery dealt with the biology of cancer in mice. He found that leukemia and cancer in the lymphatic systems of the mice resulted from a dormant virus that activated when it was exposed to radiation or chemicals that suppressed the immune system. This research laid the foundation for the modern understanding and treatment of cancers.
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Papers共 157 篇Author StatisticsCo-AuthorSimilar Experts
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Henry S. Kaplan,Anna Belinda Berry,Kristine Rinn,Erin Ellis, George Richard Birchfield,Tanya A. Wahl,Xiaoyu Liu,Mariko Tameishi,J D. Beatty,Patricia Dawson,Vivek Mehta, Anna Holman,
Ciba Foundation Symposium - The Thymus: Experimental and Clinical StudiesNovartis Foundation Symposiapp.310-334, (2008)
Ciba Foundation Symposium - Carcinogenesis: Mechanisms of ActionNovartis Foundation Symposiapp.233-248, (2008)
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