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T cells play a critical role in the immune response to the intracellular pathogen M. tuberculosis, which is estimated to infect one third of the world's population. T cells regulate the acquired immune response which controls primary infection and provide protection against exogenous reinfection. CD4+ T cells traditionally have been considered the main T cell subset responsible for regulating protective immune responses to M. tuberculosis. However, in addition to the CD4+ T cell, both gamma-delta T cell receptor bearing T cells (gamma delta cells) and CD8+ T cells have a role in protective immunity to M. tuberculosis. The study of CD4+, CD8+ and gamma delta T cell responses to M. tuberculosis is the main interest of my laboratory.
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Papers共 245 篇Author StatisticsCo-AuthorSimilar Experts
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FRONTIERS IN IMMUNOLOGY (2024): 1359178-1359178
Scott M. Reba,Qing Li,Sophia Onwuzulike,Nancy Nagy, Shane Fletcher, Kyle Parker, Rachel J. Shaw,Katharine Umphred-Wilson,Supriya Shukla,Clifford V. Harding,W. Henry Boom,Roxana E. Rojas
JCI insightno. 9 (2024)
ACS INFECTIOUS DISEASES (2024)
Journal of Infectionno. 1 (2024): 106173-106173
Bonnie A. Thiel,Kathleen C. Lundberg,Daniela Schlatzer,Jessica Jarvela,Qing Li, Rachel Shaw, Scott M. Reba, Shane Fletcher, Sara E. Beckloff,Mark R. Chance,W. Henry Boom,Richard F. Silver,
bioRxiv the preprint server for biology (2024)
PLoS pathogensno. 5 (2024): e1011675-e1011675
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