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We investigate the genes and proteins involved in biosynthesis of complex polysaccharides and glycoproteins in the plant cell wall, using arabidopsis and rice as model plants. Besides the fundamental scientific importance of these studies, understanding wall biosynthesis and regulation may allow us to develop crop plants that are more suitable feedstocks for biofuel production. Techniques used in the lab include biochemistry, spectroscopy, molecular genetics, cell biology and bioinformatics.
In the Cell Wall Biosynthesis Group we aim to:
Identify the glycosyltransferases and accessory enzymes required for biosynthesis of matrix polysaccharides and glycoproteins in the cell wall.
Develop efficient methods for biochemical analysis of cell wall biosynthetic enzymes
.
Understand the role of specific cell wall polysaccharides for growth and development, interactions with microorganisms, and abiotic stress.
Discover the regulatory and signal transduction mechanisms used by plants to dynamically control cell wall composition.
研究兴趣
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PLANT PHYSIOLOGY (2024)
Xiaoyue Chen, Graham A. Hudson, Charlotte Mineo,Bashar Amer,Edward E. K. Baidoo, Samantha A. Crowe,Yuzhong Liu,Jay D. Keasling,Henrik V. Scheller
Nature communicationsno. 1 (2023): 7101-15
Frontiers in plant science (2023): 1181035
GREEN CHEMISTRYno. 17 (2023): 6797-6808
bioRxiv : the preprint server for biology (2023)
Andy Zhou,Liam D Kirkpatrick,Izaiah J Ornelas,Lorenzo J Washington, Niklas F C Hummel, Christopher W Gee,Sophia N Tang,Collin R Barnum,Henrik V Scheller,Patrick M Shih
Yuan Zhang, Deepak Sharma,Yan Liang, Nick Downs, Fleur Dolman,Kristen Thorne,Jose Henrique Pereira,Paul D. Adams,Henrik Scheller,Malcolm O'Neill, Breeannna R Urbanowicz,Jenny C Mortimer
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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