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个人简介
Human pluripotent stem cells (hPSC), including embryonic (hESC) and induced pluripotent stem cells (iPSC), are a promising source of cells for tissue engineering applications, and the first clinical trials using these cells to treat retinal and corneal diseases are currently ongoing. However, some major challenges still exist in understanding the differentiation and function of these cells in order to enable their safe and effective translation into a clinical practice.
The main research aim for the group is to develop novel stem cell-based tools for the corneal and retinal repair through cell transplantation and ophthalmic in vitro tissue models that can be used to model human specific eye disorders. Severe ophthalmologic diseases, such as age-related macular degeneration (AMD) severely decrease the patients’ quality of life. On the other hand, hereditary retinal and corneal diseases and corneal traumas most commonly affect children and active young adults. We wish to use our expertise with important collaborators to help these patients.
The main research aim for the group is to develop novel stem cell-based tools for the corneal and retinal repair through cell transplantation and ophthalmic in vitro tissue models that can be used to model human specific eye disorders. Severe ophthalmologic diseases, such as age-related macular degeneration (AMD) severely decrease the patients’ quality of life. On the other hand, hereditary retinal and corneal diseases and corneal traumas most commonly affect children and active young adults. We wish to use our expertise with important collaborators to help these patients.
研究兴趣
论文共 181 篇作者统计合作学者相似作者
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Stem Cell Reportsno. 7 (2024): 1010-1023
Paula Puistola, Abhinav Kethiri, Antti Nurminen, Johannes Turkki, Karoliina Hopia,Susanna Miettinen,Anni Moro,Heli Skottman
ACS APPLIED MATERIALS & INTERFACESno. 13 (2024): 15761-15772
Survey of ophthalmologyno. 2 (2024): 300-301
The Journal of biological chemistryno. 6 (2023): 104770-104770
Karger Kompassno. 3 (2023): 83-101
Tanja Ilmarinen,Meri Vattulainen, Jeyalakshmi Kandhavelu, Dominique Bremond-Gignac,Daniel Aberdam,Heli Skottman
STEM CELLSno. 8 (2023)
Tanja Hyvarinen, Johanna Lotila, Iisa Tujula,Henna Jantti,Sohvi Ohtonen,Heli Skottman,Laura Airas,Tarja Malm,Susanna Narkilahti,Sanna Hagman
MULTIPLE SCLEROSIS JOURNAL (2023): 215-215
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INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCEno. 8 (2023)
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