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Our research focuses on the role of the central brain mechanisms on neurohormonal adjustments in cardiovascular regulation in the setting of experimental chronic heart failure. We are interested in the role of substances such as angiotensin II, ACE2, nitric oxide and reactive oxidant stress as important mediators of sympathetic excitation in the setting of chronic heart failure. Molecular, cellular and whole animal techniques are used to understand abnormal cardiovascular and neural regulation in heart failure. In addition, we are extremely interested in the role of exercise training in ameliorating some of the abnormalities we have found in the central nervous system of animals with heart failure.
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PHYSIOLOGYno. S1 (2023)
Anjali Bhat, Kanika Sharma, Will Bruening, Brenden Lofgren,Li Yu,Tara Rudebush, Vikas Kumar,Irving Zucker,Lie Gao
PHYSIOLOGY (2023)
Journal of Hypertensionno. Suppl 3 (2023): e184-e184
PHYSIOLOGYno. S1 (2023)
FRONTIERS IN PHYSIOLOGY (2023): 1288907-1288907
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