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Bio
In the Powrie Lab, my research focuses on host-microbe interactions that regulate health and disease. The gut is the primary site of host-commensal symbiosis, but disequilibrium can drive inflammation and damaging systemic immune responses. Indeed, this gut-joint axis has been implicated in inflammatory arthritis, and imbalances in the microbial community have been described in patients. As a part of the Inflammatory Arthritis Microbiome Consortium, cross-disciplinary approaches in next-generation sequencing, multi-omic analyses, and microbiota cultivation will be integrated into experimental systems. The ultimate goal of this research is to identify novel paradigms of microbiota-regulated immune responses, with the potential for novel diagnostic markers and therapeutic interventions.
Research Interests
Papers共 10 篇Author StatisticsCo-AuthorSimilar Experts
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India Brough,Kelsey Thompson, Ciara Latore,Frank Penkava, Chelsea Regan,Claire Pearson,Hui Shi,Anna Ridley,Davide Simone,Lilian Lam,Samuel Bullers, Caroline Moussa,
Discovery Immunology (2024)
Kelsey N. S. Thompson,Kevin S. E. Bonham,Nicholas E. J. Ilott,Graham J. Britton, Paula J. Colmenero,Samuel J. J. Bullers,Lauren J. McIver,Siyuan H. Ma,Long H. Nguyen,Andrew Filer, India Brough,Claire Pearson,
SCIENCE TRANSLATIONAL MEDICINEno. 706 (2023): eabn4722-eabn4722
Cell host & microbeno. 2 (2018): 296-307.e7
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