基本信息
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Bio
Dr. Kaufman's research has focused on the development of oncolytic viruses and immunotherapy for the treatment of melanoma and other types of cutaneous malignancies. His lab has contributed to understanding how viruses induce immunogenic cell death and initiate host anti-tumor immunity. He led the first randomized phase III clinical trial of an oncolytic herpes simplex type 1 (HSV-1) virus encoding GM-CSF in patients with advanced melanoma, which resulted in FDA approval of the first oncolytic virus in cancer. He also helped establish the role of anti-PD-L1 treatment for patients with advanced Merkel cell carcinoma. He continues to focus on how to integrate oncolytic viruses into combination immunotherapy regimens to enhance systemic immunity and improve therapeutic responses in patients with cancer.
Research Interests
Papers共 559 篇Author StatisticsCo-AuthorSimilar Experts
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Cancerno. 15 (2024): 2670-2682
The American surgeonpp.31348241248785-31348241248785, (2024)
Asma S. Khelifa, Katherine L. Lothstein, Masaya Miyamoto, Rob Tighe,Sailaja Battula,Howard L. Kaufman,Jeffrey Schlom,Sofia R. Gameiro
Cancer Researchno. 6_Supplement (2024): 4082-4082
Hongbin Wang, Mia Borlongan,Howard L Kaufman, Uyen Le,Hans J Nauwynck,Samuel D Rabkin,Dipongkor Saha
Journal for immunotherapy of cancerno. 5 (2024)
Jason J. Luke,Diwakar Davar,Robert H. Andtbacka, Nina Bhardwaj, Joshua D. Brody, Jason Chesney, Robert Coffin, Thierry de Baere, Tanja D. de Gruijl, Matthew Fury,Gregory Goldmacher,Kevin J. Harrington,
JOURNAL FOR IMMUNOTHERAPY OF CANCERno. 4 (2024)
Cancer Researchno. 6_Supplement (2024): 2468-2468
Serena Vilasi,David Miller,Howard Kaufman,Kevin Emerick,Sophia Shalhout,Emily Kim, Vishal Patel, Khalid Garmen,Sameer Gupta,Isaac Brownell
Journal of Cutaneous Oncologyno. 1 (2023)
Journal of translational medicineno. 1 (2023): 483-11
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Author Statistics
#Papers: 567
#Citation: 31432
H-Index: 83
G-Index: 169
Sociability: 8
Diversity: 0
Activity: 2
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