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The Karch working group focuses on the characterization of Enterohemorrhagic Escherichia coli (EHEC) and the diseases it causes (diarrhoeal disease, hemolytic uremic syndrome, neurological complications). The pathological mechanisms of intestinal and extraintestinal injury have not been fully elucidated. Receptor-mediated and nonspecific adhesion of EHECs is considered an important prerequisite for the establishment of intestinal infection. In the Karch working group, the mechanisms by which these pathogens attach to the intestinal mucosa and the cellular injury mode of action of the virulence factors produced by EHEC are being investigated.
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论文共 321 篇作者统计合作学者相似作者
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Medizinische Mikrobiologie und Infektiologiepp.299-335, (2020)
Carbohydrate Polymers (2019): 323-333
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