Hiten D Mistry

My main research interests are in the pathophysiology of the hypertensive diseases of pregnancy and intrauterine growth restriction. Pre-eclampsia remains a common disorder in pregnancy, affecting 3-5% of all UK pregnancies. Pre-eclampsia is a state of elevated oxidative stress; reduced placental perfusion or ischaemic reperfusion play a critical role in excessive generation of reactive oxygen species (ROS), which are thought to initiate a cascade of events in susceptible individuals leading to maternal oxidative stress and endothelial cell dysfunction.