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个人简介
My goal is an academic research career as a principal investigator in neuroscience. I conducted my undergraduate research in Dr. Irving E. Vega’s laboratory at the University of Puerto Rico-Rio Piedras campus. In Dr. Vega’s laboratory, I characterized proteome level changes associated with development of tau-mediated neurodegeneration, with the ultimate goal of gaining insight into new ways to treat this class of disorders, including Alzheimer’s disease. I also worked in the summer of 2010 in Dr. Anthony Windebank’s lab at the Mayo Clinic in Rochester, Minnesota, as part of Summer Undergraduate Research Fellowship (SURF) program. There, I initiated a new project to examine the effects of the chemotherapy drug Cisplatin in Zebrafish, and learned that apoptosis appears to be the preferred death pathway over necrosis following exposure of whole fish to Cisplatin, which preferentially attacks neurons over other cell types. Taken together, my undergraduate research experiences were highly rewarding and prompted me to pursue graduate studies in neuroscience. In my first year, I was awarded an NSF Fellowship (NSF GRFP). For my thesis work, I joined Dr. Andrew Pieper’s laboratory in the departments of Psychiatry and Biochemistry. My work has centered around molecular mechanisms of neuronal cell death, involving both calcium signaling via the Cav1.2 subunit of L-type calcium channels, and characterization of the neuroprotective efficacy of the novel P7C3 class of neuroprotective aminopropyl carbazole molecules discovered and developed in the Pieper laboratory. I recently joined Dr. Bear’s lab for my postdoctoral training, where I currently study the physiology of synaptic plasticity, and how experience and pharmacological treatments can impact this process. I hope this works further expands our knowledge about the mechanisms of learning and memory in the healthy brain, and diverse neurological and psychiatric disorders.
研究兴趣
论文共 21 篇作者统计合作学者相似作者
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Héctor De Jesús-Cortés,Daniel A. Bowen, Francis Reilly-Andújar, Sophie Lu,Eric D. Gaier,Mark F. Bear
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Edwin Vazquez-Rosa,Min-Kyoo Shin,Coral Cintron-Perez,Kalyani Chaubey,Sarah Barker, Adora Ezepue, Kate Lindley, Youngmin Yu, Ayush Vyas, Jiwon Hyung,John Broussard,Hector De Jesus-Cortes,
BRAIN INJURY (2023): 56-56
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Anni S Lee,Héctor De Jesús-Cortés,Zeeba D Kabir,Whitney Knobbe, Madeline Orr,Caitlin Burgdorf,Paula Huntington,Latisha McDaniel,Jeremiah K Britt, Franz Hoffmann,Daniel J Brat,Anjali M Rajadhyaksha,
Natureno. 7570 (2015): 552-552
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