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T cells play critical roles in the adaptive immune system. The overall research interest of Deng lab is to investigate the mechanism of T cell activation, tolerance and engineering for effective immunotherapy. We use genetic and immunological approaches to determine the signaling pathways regulating T cell function in models of autoimmunity and tumor immunity. In addition, we collaborate extensively with clinics in analyzing the T cell function of patients. We are interested in studies aimed at translating fundamental understanding of T cell function into new therapies for autoimmune diseases and cancer.
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论文共 17 篇作者统计合作学者相似作者
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Lena Sophie Mayer, Robert J. Orlowski,Josephine Giles,Joseph L. Benci,Gavin Ellis,Guoping Deng,John Attanasio,Zeyu Chen,Bertram Bengsch, Omar Kahn,Sasikanth Manne,Ramin S. Herati,
AMERICAN JOURNAL OF CLINICAL AND EXPERIMENTAL IMMUNOLOGYno. 5 (2018): 81-87
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