基本信息
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Career Trajectory
Bio
Dr. Guofeng Lou studied the molecular mechanisms of modified rhaFGF, which was mediated by the phosphorylation of GSK3β, as a therapeutic strategy for Alzheimer's disease (AD) in his Ph.D program at Jinan University, China. He then investigated the role of VAAT and the interplay between VAAT and 5-HT in gene knock-out mouse brain tissues during his first Postdoctoral research at Uppsala University, Sweden. In the Fang laboratory (UiO), he is very interested in studying the molecular mechanisms of mitochondrial autophagy (mitophagy) and its roles in AD. More specifically, he is using multiple laboratory models, including C. elegans, novel transgenic mouse models, as well as human iPSCs, to elucidate the molecular basis of impaired mitochondrial motility and defective mitophagy in AD.
Research Interests
Papers共 13 篇Author StatisticsCo-AuthorSimilar Experts
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Qing-Qing Xie,Xiao Feng, Yi-Υun Huang,Nian Fang,Hua Yi,Zi-Jian Wang, Qiao-Υu Cao,Guo-Feng Lou,Jun-Ping Pan,Yang Hu,Fang-Cheng Li,Qing Zheng,
Trends in Molecular Medicineno. 1 (2020): 8-20
Materials Science and Engineering: C (2017): 237
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#Papers: 13
#Citation: 317
H-Index: 8
G-Index: 11
Sociability: 5
Diversity: 2
Activity: 13
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