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Bio
Prior to join Cancer Immunology department at Genentech (Roche Group), I worked on innate immune biology to identify new mechanisms responsible for lung inflammation and injury and to develop novel therapies to combat lung disease. More specifically I worked on neutrophil and platelet biology applied to a variety of pulmonary disease states including acute lung injury and cystic fibrosis. My studies also focused on the role of the pulmonary circulation in platelet biogenesis and the hematopoietic potential of the lung.
At Genentech I have been working on the development and design of a new tumor model that will enable real-time quantification of immune cell recruitment, localization, and activation during anti-tumor immune response. This new tumor implantation technique called STAMP, allow high-throughput in vivo Imaging and it is used as a tool to study the role of tumor microenvironment in the response to cancer immunotherapies. By combining live imaging and next generation sequencing (NGS), I aim to identify unique pathways that control the immune landscape of tumors and discover novel molecular targets for designing new efficacious therapies.
Research Interests
Papers共 30 篇Author StatisticsCo-AuthorSimilar Experts
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CANCER RESEARCHno. 7 (2023)
Guadalupe Ortiz-Muñoz,Markus Brown,Catherine B. Carbone,Ximo Pechuan-Jorge,Vincent Rouilly, Henrik Lindberg,Alex T. Ritter,Gautham Raghupathi, Qianbo Sun, Tess Nicotra,Shreya R. Mantri,Angela Yang,
NATUREno. 7966 (2023): 827-833
Cancer Researchno. 7_Supplement (2023): 4439-4439
Guadalupe Ortiz-Muñoz, Mark R. Brown,Catherine B. Carbone,Ximo Pechuan-Jorge, Ritter At,Darya Orlova, Mantri,Annan Yang,Jonas Doerr,Sanjeev Mariathasan, Y Wang,Shannon J. Turley,
bioRxiv (Cold Spring Harbor Laboratory) (2021)
biorxiv(2021)
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