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Career Trajectory
Bio
I study the evolution of genes and genomes with the broad aim of understanding the origins of biological diversity. My approach focuses on changes in the expression of genes using both empirical and computational approaches and spans scales of biological organization from single nucleotides through gene networks to entire genomes. At the finer end of this spectrum of scale, I am focusing on understanding the functional consequences and fitness components of specific genetic variants within regulatory sequences of several genes associated with ecologically relevant traits. At the other end of the scale, I am developing molecular and analytical methods to detect changes in gene function throughout entire genomes, including statistical frameworks for detecting natural selection on regulatory elements and empirical approaches to identify functional variation in transcriptional regulation. At intermediate scales, I am investigating functional variation within a dense gene network in the context of wild populations and natural perturbations. My research leverages the advantages of several different model systems, but primarily focuses on sea urchins and primates (including humans).
Research Interests
Papers共 248 篇Author StatisticsCo-AuthorSimilar Experts
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bioRxiv : the preprint server for biology (2024)
bioRxiv : the preprint server for biology (2024)
Jing Liu,Federica Mosti, Hanzhi T. Zhao, Jesus E. Sotelo-Fonseca,Carla F. Escobar-Tomlienovich, Davoneshia Lollis,Camila M. Musso, Yiwei Mao,Abdull J. Massri, Hannah M. Doll,Andre M. Sousa,Gregory A. Wray,
biorxiv(2024)
Brennan D. McDonald,Abdull J. Massri, Alejandro Berrio Escobar,Maria Byrne,David R. McClay,Gregory A. Wray
biorxiv(2024)
Genome Biology and Evolutionno. 6 (2023)
Malaria Journalno. 1 (2023): 1-9
EvoDevono. 1 (2023): 10-13
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