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Bio
My research focuses on the chemistry and biology of microbial natural products. This encompasses natural product discovery, elucidation of biosynthetic pathways, creation of natural product analogues and novel molecular scaffolds via synthetic biology, and the mechanism of action and biological function of natural products.
Our approach is highly interdisciplinary and employs numerous complementary techniques, including chemical synthesis and analysis, molecular genetic manipulation, enzymology, protein mass spectrometry, structural biology (X-ray crystallography, protein NMR spectroscopy and single particle cryo-electron microscopy), bioinformatics, molecular modelling, and bioactivity assays.
Research Interests
Papers共 211 篇Author StatisticsCo-AuthorSimilar Experts
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRYno. 26 (2024): 14760-14768
Sarah R. Messenger, Edward M. R. McGuinniety,Luke J. Stevenson,Jeremy G. Owen,Gregory L. Challis,David F. Ackerley,Mark J. Calcott
Nature Chemical Biologyno. 2 (2024): 251-260
Cameron Baines, Jacob Sargeant,Christopher D Fage, Hannah Pugh,Lona M Alkhalaf,Gregory L Challis,Neil J Oldham
Journal of the American Society for Mass Spectrometryno. 7 (2024): 1490-1496
Journal of the American Chemical Societyno. 9 (2024): 6114-6124
crossref(2024)
Christopher D. Fage,Munro Passmore,Ben P. Tatman, Helen G Smith,Xinyun Jian, Upeksha C Dissanayake,G. Andrés Cisneros,Gregory L. Challis,Józef Lewandowski,Matthew Jenner
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Sarah R. Messenger, Edward M. R. McGuinniety,Luke J. Stevenson,Jeremy G. Owen,Gregory L. Challis,David F. Ackerley,Mark J. Calcott
bioRxiv (Cold Spring Harbor Laboratory) (2023)
Christopher D Fage,Munro Passmore,Ben P Tatman, Helen G Smith,Xinyun Jian, Upeksha C Dissanayake,G Andrés Cisneros,Gregory L Challis,Józef R Lewandowski,Matthew Jenner
bioRxiv : the preprint server for biology (2023)
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