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My research involves identifying gene regulatory elements across the genome to help us understand how chromatin structure dictates cell function and fate. For the last 30 years, mapping chromatin accessible sites has been the gold standard method to identify the location of active regulatory elements, including promoters, enhancers, silencers, and locus control regions. I have developed technologies that can identify most DNase I hypersensitive sites from potentially any cell type from any species with a sequenced genome. We are combining this data with other wet-lab and computational data types to better understand how these regulatory regions control global gene expression in a set of diverse tissues (normal and diseased) representative of the human body.
Research Interests
Papers共 287 篇Author StatisticsCo-AuthorSimilar Experts
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Brian D. Cosgrove, Lexi R. Bounds, Carson Key Taylor, Alan L. Su, Anthony J. Rizzo,Alejandro Barrera,Gregory E. Crawford,Brenton D. Hoffman,Charles A. Gersbach
bioRxiv the preprint server for biology (2024)
SUPPORTIVE CARE IN CANCERno. 4 (2024)
INTERNAL MEDICINE JOURNALno. 3 (2024): 523-524
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancerno. 4 (2024): 228-228
Hannah R. Wardill, Luke T. Wooley, Olivia M. Bellas, Katrina Cao, Courtney B. Cross,Madele van Dyk,Ganessan Kichenadasse,Joanne M. Bowen,Andrew C. W. Zannettino,Sepehr Shakib,Gregory B. Crawford, Jaroslav Boublik,
British Journal of Cancerno. 1 (2024): 19-30
Supportive Care in Cancerno. 4 (2024): 1-10
E. Keats Shwab, Daniel C. Gingerich, Zhaohui Man,Julia Gamache,Melanie E. Garrett,Gregory E. Crawford,Allison E. Ashley-Koch,Geidy E. Serrano,Thomas G. Beach,Michael W. Lutz,Ornit Chiba-Falek
Acta Neuropathologica Communicationsno. 1 (2024): 1-30
Sheryn Tan, Jeng Swen Ng,Charis Tang,Brandon Stretton,Joshua Kovoor,Aashray Gupta, Thomson Delloso, Tony Zhang,Rudy Goh,Shaddy El-Masri,Michelle Kiley, Ian Maddocks,
Wancen Mu,Tianyou Luo,Alejandro Barrera, Lexi R Bounds,Tyler S Klann, Maria Ter Weele,Julien Bryois,Gregory E Crawford,Patrick F Sullivan,Charles A Gersbach,Michael I Love,Yun Li
bioRxiv : the preprint server for biology (2024)
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