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Bio
My research focus has been on improving treatments for older patients who have acute and chronic leukemia. My colleagues and I pioneered the use of reduced-intensity conditioning regimens for older or more debilitated patients with blood cancers. Before this discovery, older patients with these diseases were rarely considered candidates for stem cell transplantation procedures using donor cells because of the toxic effects of high-dose chemotherapy. The development of these less intense and less toxic regimens has allowed us to perform transplants for older patients in a safe and effective manner and has changed the standard of care throughout the world. I plan to continue this research in the context of the pioneering T cell depletion techniques developed at Memorial Sloan Kettering. This new approach has dramatically reduced the risk of graft-versus-host disease, a serious complication of donor stem cell transplantation. Disease recurrence after transplantation remains an important cause of treatment failure, and I am a proponent of post-transplant maintenance therapies using a variety of targeted therapies, which we are continuing to explore at Memorial Sloan Kettering
Research Interests
Papers共 1594 篇Author StatisticsCo-AuthorSimilar Experts
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TRANSPLANTATION AND CELLULAR THERAPYno. 1 (2024): 81-92
Rachel Lorenc,Roni Shouval,Jessica R. Flynn,Sean M. Devlin,Amethyst Saldia,Alejandro Luna De Abia,Magdalena Corona De Lapuerta,Ana Alarcon Tomas, Giulio Cassanello,Lori A. Leslie,Kai Rejeski,Richard J. Lin,
Transplantation and Cellular Therapy (2024)
British journal of haematologyno. 4 (2024): 1429-1438
Leland L Metheny,Ronald Sobecks,Christina Cho,Pingfu Fu,Seunghee Margevicius,Jiasheng Wang, Lisa Ciarrone, Shelby Kopp, Robin D Convents,Navneet Majhail,Paolo F Caimi,Folashade Otegbeye,
Blood advancesno. 6 (2024): 1384-1391
Transplantation and Cellular Therapyno. 2 (2024): S348
Madhavi Lakkaraja,Audrey Mauguen,Devin McAvoy,Kinga Hosszu, Katina H Singh, Esther H Vidal, Dr. Valerie Stewart, Gabrielle Schmidt,John E Levine,Miguel-Angel Perales,Sergio A. Giralt, K. Scott Baker,
Transplantation and Cellular Therapyno. 2 (2024): S439
Transplantation and Cellular Therapyno. 2 (2024): S48-S49
Transplantation and Cellular Therapyno. 2 (2024): S145
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Author Statistics
#Papers: 1582
#Citation: 45773
H-Index: 107
G-Index: 183
Sociability: 9
Diversity: 0
Activity: 10
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