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Our research focuses on the interacting states of sleep, pain and general anesthesia from a systems neuroscience perspective. Specifically, we use rodent models of inflammatory and post-surgical pain to better understand how disrupted sleep can worsen ongoing pain and lead to the development of chronic pain. An additional line of investigation seeks to advance our understanding of the mechanisms underlying the loss of consciousness during states of sleep, sedation and general anesthesia. Our laboratory uses transgenic mice models, behavioral assays, neurophysiological recordings, brain connectivity analysis, neurochemistry, calcium imaging, and chemogenetic and pharmacological tools to probe neural networks controlling sleep, wakefulness and nociception.
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论文共 66 篇作者统计合作学者相似作者
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Brian H Silverstein, Nicholas Kolbman,Amanda Nelson, Tiecheng Liu, Peter Guzzo, Jim Gilligan,UnCheol Lee,George A Mashour,Giancarlo Vanini,Dinesh Pal
bioRxiv : the preprint server for biology (2024)
EUROPEAN JOURNAL OF NEUROSCIENCEno. 4 (2024): 483-501
Brian H Silverstein,Anjum Parkar,Trent Groenhout, Zuzanna Fracz,Anna M Fryzel, Christopher W Fields,Amanda Nelson,Tiecheng Liu,Giancarlo Vanini,George A Mashour,Dinesh Pal
British journal of anaesthesiano. 6 (2023): 1248-1259
Nicholas Kolbman, Tiecheng Liu, Peter Guzzo, Jim Gilligan,George A Mashour,Giancarlo Vanini,Dinesh Pal
Current biology : CBno. 24 (2023): R1282-R1283
Phillip E Vlisides,Jacqueline Ragheb,Amy McKinney,Graciela Mentz,Nathan Runstadler, Selena Martinez, Elizabeth Jewell,UnCheol Lee,Giancarlo Vanini,Eva M Schmitt,Sharon K Inouye,George A Mashour
BMJ openno. 5 (2023): e073945-e073945
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Nicholas Kolbman, Tiecheng Liu, Peter R. Guzzo, James Gilligan,George A. Mashour,Giancarlo Vanini,Dinesh Pal
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Methodological Approaches for Sleep and Vigilance Researchpp.1-16, (2022)
Methodological Approaches for Sleep and Vigilance Researchpp.17-32, (2022)
CANNABINOIDS AND SLEEP: MOLECULAR, FUNCTIONAL AND CLINICAL ASPECTS (2021): 65-82
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