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Professor Gerard Evan and his team in the Department of Biochemistry are studying the genes that drive the development and growth of cancer, called oncogenes.
Professor Evan’s work focuses on a gene called Myc, which helps tumours grow, spread and develop a blood supply. Many scientists think that drugs targeting Myc could be a good way to treat cancer. But Myc has many different roles within healthy cells, as well as in cancer cells.
Professor Evan and his team are figuring out exactly how Myc works, both in healthy tissue and in several types of cancer, including lung and pancreatic cancers. They are also testing drugs that can block Myc as well as searching for other genes that work with it, which could also be good targets for future cancer treatments.
Professor Evan’s work focuses on a gene called Myc, which helps tumours grow, spread and develop a blood supply. Many scientists think that drugs targeting Myc could be a good way to treat cancer. But Myc has many different roles within healthy cells, as well as in cancer cells.
Professor Evan and his team are figuring out exactly how Myc works, both in healthy tissue and in several types of cancer, including lung and pancreatic cancers. They are also testing drugs that can block Myc as well as searching for other genes that work with it, which could also be good targets for future cancer treatments.
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Cellno. 7 (2024): 1589-1616
David Propper,Erkut Borazanci, Peter J. O'Dwyer,Daniel Von Hoff, Joseph Hartlebury,Corina E. Antal,Gerard I. Evan,HaiYong Han,Michael Downes,Ronald Evans,Joshua Rabinowitz, Emmanuel Petricoin,
Cancer Researchno. 7_Supplement (2024)
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Christopher Abbosh,Alexander M Frankell,Thomas Harrison,Judit Kisistok,Aaron Garnett, Laura Johnson,Selvaraju Veeriah, Mike Moreau, Adrian Chesh,Tafadzwa L Chaunzwa,Jakob Weiss,Morgan R Schroeder,
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