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1.Wang, J. Stephens, G.L., and Howell, M., Profiling of Atopic Dermatitis, Psoriasis, and Contact Dermatitis Patient Sera to Identify Unique Proteomic Disease Signatures. In press. Clinical and Experimental Immunology. 2017.
2.Rieder, S. Qadri, A. Kolbeck R. Stephens, G.L., A Novel Member of the B7 Family Promotes Tumor Immunity in Exhausted T Cells. Manuscript in preparation. 2016.
3.Stephens, G.L., Zeng, R., Guo, X., Steven Eck, Yuling Wu, Liangwei Wang, Warren Greth, Gabor Illei, Wendy I. White., A Single Cell Analysis of Leukocytes Subsets in Patient Treated in a Phase II Clinical Study with Anifrolumab. Manuscript in preparation. 2016.
4.An L.L., Gorman J.V., Stephens G., Swerdlow B., Warrener P., Bonnell J., Mustelin T., Fung M., Kolbeck R.. Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways. Scientific Reports. 6, 2016.
5.Mazor Y., Hansen A., Yang C., Chowdhury P.S., Wang J., Stephens G., Wu H., Dall'Acqua W.F.. Insights into the molecular basis of a bispecific antibody's target selectivity. mAbs. 2015, 7(3): 461-9.
6.Tkaczyk, C., Hamilton, M., Datta, V., Yang, X.P., Stephens, G.L, Sadowska, A., Hua, L., Barnes, A., O’Day, T., Stover, C. K., Sellman, B.. Staphylococcus aureus alpha toxin modulates the innate and adaptive immune responses in a mouse dermonecrosis model. PLOS One. 2013.
7.Ephrem, A., Epstein, A., Stephens, G.L., Thornton, A.M., Glass, D., Shevach, E.M. Modulation of Teff/Treg Function by GITR Signaling is Context Dependent. Eur J Immunol. 2013 May 30.
8.Stephens, G.L.*, Wang, Q.*, Swerdlow, B., Bhat, G., Kolbeck, R., Fung, M. Kynurenine 3-Monooxygenase Mediates Inhibition of Th17 Differentiation via Catabolism of Endogenous Aryl Hydrocarbon Receptor Ligands. Eur J Immunol. 2013 Apr 9.
*Joint 1st author publication
9.Karnell J.L., Karnell F.G., Stephens G.L., Rajan B., Morehouse C., Li Y., Swerdlow B., Wilson M., Goldbach-Mansky R., Groves C., Coyle A.J., Herbst R., Ettinger R. Mycophenolic acid differentially impacts B cell function depending on the stage of differentiation. J Immunol. 2011 Oct 1;187(7):3603-12.
10.Stephens G.L., Swerdlow B., Benjamin E., Coyle A.J., Humbles A., Kolbeck R., Fung M. IL-9 is a Th17-derived cytokine that limits pathogenic activity in organ-specific autoimmune disease. Eur J Immunol. 2011 Apr;41(4):952-62.
11.Kolbeck, R., Kozhich, A., Koike, M., Peng, L., Busse, W., Andersson, C.K., Damschroder, M.M., Reed, J.L., Woods, R., Dall’Acqua, W.W., Stephens, G.L., Erjefalt, J.S., Humbles, A., Kiener, P.A., Spitalny, G.L., Mackay, C.R., Molfino, N.A., and Coyle, A.J.: MEDI-563, A Humanized Anti-IL-5Rα Monoclonal Antibody With Enhanced Effector Function Mediates Reversible Peripheral Blood Eosinophil Depletion in Patients with Mild Asthma. J Allergy Clin Immunol. 2010 Jun; 125(6):1344-1353.
12.Elias, K.M., Laurence, A., Davidson T.S., Stephens G., Kanno Y., Shevach E.M., O' Shea J.J.: Retinoic acid inhibits Th17 polarization and enhances FoxP3 expression through a Stat-3/Stat-5 independent signaling pathway. Blood. Oct 19, 2007.
13.Stephens, G.L. and Shevach, E.M.: FoxP3+ Regulatory T Cells: Selfishness under Scrutiny. Immunity. 27: 417, 2007.
14.Stephens, G.L., Andersson, J. and Shevach, E.M.: Distinct Subsets of FoxP3+ Regulatory T Cells Participate in the Control of Immune Responses. J. Immunol. June 1, 2007.
15.Tough, D.F., Sprent, J. and Stephens, G.L. Measurement of T and B Cell Turnover with Bromodeoxyuridine. J. Coligan, and A. M. Kruisbeek, and D. H. Margulies, and E. M. Shevach, and W. Strober, eds. Current Protocols in Immunology 4.7.1-4.7.9. John Wiley and Sons, New York.. Current Protocols in Immunology. 2007.
16.Andersson, J., Stefanova I., Stephens, G.L., and Shevach, E.M.: CD4+CD25+ regulatory T cells are activated in vivo by recognition of self. Int. Immunol. March 15, 2007.
17.Yao Z., Kanno Y., Kerenyi M., Stephens G., Durant L., Watford W.T., Laurence A, Robinson G.W., Shevach E.M., Morrigl R., Hennighausen L., Wu C, O'Shea J.J.: Nonredundant roles for Stat5a/b in directly regulating Foxp3. Blood. Jan 16, 2007.
18.Shevach E.M., DiPaolo R.A., Andersson J., Zhao D.M., Stephens G.L., Thornton, A.M..: The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol Rev. 212: 60, 2006.
19.Shevach E.M. and Stephens G.L. The GITR-GITRL interaction: co-stimulation or contrasuppression of regulatory activity? Nat Rev Immunol. 6(8): 613, 2006.
20.Valencia X., Stephens G., Goldbach-Mansky R., Wilson M., Shevach E.M., Lipsky P.E.: TNF downmodulates the function of human CD4+CD25hi T-regulatory cells. Blood. 108(1):253, 2006.
21.Stephens, G.L., McHugh, R. S., Whitters, M. J., Young, D. A., Luxenberg, D., Carreno, B. M., Collins, M., and Shevach, E. M.: Engagement of glucocorticoid-induced TNFR family-related receptor on effect T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells. J. Immunol. 173: 5008, 2004.
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J Wang,M Suárez-Fariñas,Y Estrada, M L Parker,L Greenlees,G Stephens,J Krueger, E Guttman-Yassky,M D Howell
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Ling-Ling An, Jacob V. Gorman,Geoffrey Stephens, Bonnie Swerdlow,Paul Warrener,Jessica Bonnell, Tomas Mustelin,Michael Fung,Roland Kolbeck
mAbsno. 3 (2015): 461-9
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