Dr. Geoffrey Hill is a physician-scientist who specializes in blood stem cell transplantation. He is one of the top authorities on the transplant complication known as graft-vs.-host disease, or GVHD. In particular, Dr. Hill focuses on the immunological mechanisms initiating both acute and chronic forms of GVHD. Acute GVHD in the gastrointestinal tract is the greatest cause of transplant-related mortality while chronic GVHD is the greatest cause of illness and debility in transplant survivors. Dr Hill aims to minimize GVHD and make transplantation more tolerable to patients. He also works to reduce infection, relapse and immunological rejection of the transplanted cells. His lab research is demonstrating how cell-signaling molecules called cytokines direct immune cells that play critical roles in transplant outcomes. His team’s findings have led to new therapies for GVHD and helped establish new standards of care for transplant patients. With Fred Hutch colleagues, he is now developing methods to integrate transplantation with other forms of cancer immunotherapy like T-cell therapy. Dr. Hill also cares for patients with blood cancers like leukemia.