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Our group is studying molecular regulators of normal mammary gland development and cancer, with a particular interest in understanding how mammary stem cells and their progeny contribute to the mammary epithelial cell hierarchy and breast cancer. This work led to the discovery of RANK-positive progenitors as a target for breast cancer prevention in BRCA1 mutation carriers. Our laboratory is also using patient derived xenograft (PDX) and tumor organoid models to test promising anti-cancer agents.
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论文共 258 篇作者统计合作学者相似作者
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Nature Cell Biologyno. 1 (2024): 138-152
Nature medicinepp.1-1, (2024)
Dilanka De Silva,Lesley Stafford,Anita Skandarajah,Michelle Sinclair,Lisa Devereux,Kirsten Hogg,Maira Kentwell,Allan Park,luxi Lal,Magnus Zethoven, Madawa Jayawardena,Fiona Chan,
Cancer Researchno. 9_Supplement (2024): PO1-09
Meng-Xiao Luo,Tania Tan,Marie Trussart, Annika Poch, Thi Minh Hanh Nguyen,Terence P. Speed,Damien G. Hicks, Esther Bandala-Sanchez,Hongke Peng,Stéphane Chappaz, Charlotte Slade,Daniel T Utzschneider,
biorxiv(2024)
Rachel Michaelson-Cohen, Joan Brunet, Rita Katharina Schmutzler, D. Gareth Evans,Michael Gnant,Dominik Hlauschek, Aleksandra Mystek,Nizar Bhulani,Geoff Lindeman, Christian Singer,Judy Garber
EUROPEAN JOURNAL OF HUMAN GENETICS (2024): 544-545
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Nature medicinepp.1-9, (2024)
Growth factors (Chur, Switzerland)no. 2 (2024): 49-61
Cancer Researchno. 9_Supplement (2024): PO2-08
crossref(2023)
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