基本信息
views: 264
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Michael H. Gelb studied chemistry and biochemistry as an undergraduate at the University of California at Davis. His Ph.D. studies with Stephen G. Sligar at Yale University led to a better understanding of the catalytic mechanism of cytochrome P450. As an American Cancer Society Postdoctoral Fellow in the laboratory of the late Robert H. Abeles at Brandeis University, Gelb studied a variety of mechanism-based inactivators of serine proteases and developed fluorinated ketones as tight-binding inhibitors of several classes of proteases. In 1985 Gelb became a faculty member in the Departments of Chemistry and Biochemistry at the University of Washington. Major breakthroughs in the group include the development of methods to properly analyze the action of enzymes on membrane surfaces, the discovery of protein prenylation (farnesylation and geranylgeranylation) in mammalian cells (together with John A. Glomset), and the development of Isotope-Coded Affinity Tags (ICAT reagents) for proteomic applications (together with Ruedi Aebersold).
Research Interests
Papers共 995 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Molecular Therapyno. 7 (2024): 2207-2222
MOLECULAR GENETICS AND METABOLISMno. 2 (2024)
MOLECULAR GENETICS AND METABOLISMno. 2 (2024)
MOLECULAR GENETICS AND METABOLISMno. 1 (2024): 108436-108436
Molecular genetics and metabolismno. 1 (2024): 108352-108352
Christian Posern, Benjamin Dreyer,Sarah L Maier,Florian Eichler,Michael H Gelb,René Santer,Annette Bley,Simona Murko
Molecular genetics and metabolismno. 2 (2024): 108489-108489
Molecular Genetics and Metabolismno. 4 (2024): 108517-108517
Yuexuan Liu,Michael H. Gelb
MOLECULAR GENETICS AND METABOLISMno. 1 (2024): 108105-108105
Christian Posern, Benjamin Dreyer,Sarah L. Maier,Florian Eichler,Michael H. Gelb,René Santer,Annette Bley,Simona Murko
Molecular Genetics and Metabolismpp.108489, (2024)
Nicole R. Kelly,Joseph J. Orsini,Aaron J. Goldenberg, Niamh S. Mulrooney,Natalie A. Boychuk, Megan J. Clarke, Katrina Paleologos,Monica M. Martin,Hannah McNeight,Michele Caggana,Sean M. Bailey, Lisa R. Eiland,
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn