基本信息
views: 20
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
Vascular causes of cognitive impairment and dementia is my main area of interest. At the UMC Brain Center of the University Medical Centre Utrecht, the Netherlands, I have established a multidisciplinary research program on vascular cognitive impairment (VCI) and small vessel diseases (SVDs). Our particular focus is on novel imaging markers of VCI and SVDs, that can improve diagnosis and support development of treatment. We implement the latest insights in our VCI clinic.
Using the unique properties of high field 7T-MRI we have been able – for the first time -to detect cerebral microinfarcts in vivo and we have subsequently translated the technique to 3T-MRI, and published standards on microinfarct detection in The Lancet Neurology. Currently we 1) explore small vessel disease in VCI at the level of the small vessels themselves, through novel measures of small vessel structure and function at 7T MRI, thus getting to the core disease processes and 2) improve understanding of the functional impact of vascular lesions through large multicenter lesion symptom mapping studies (through the META VCI MAP consortium; first results in The Lancet Neurology, 2021) and white matter network studies using diffusion MRI.
Another topic of interest is cognitive impairment in relation to diabetes. We have characterized trajectories and stages of cognitive dysfunction and established underlying structural brain changes with MRI. I served as PI of two large multicentre RCTs on prevention of cognitive decline in patients with in type 2 diabetes. I was also involved in clinical guidelines. From 2016, I serve as a consultant on the brain MRI and cognition outcomes of the Diabetes Control & Complications Trial (DCCT)/Epidemiology of Diabetes Interventions and Complications Study (EDIC) Cohort”, and several other NIH funded programs.
I work with international collaborators in Munich, Edinburgh, Seoul, Hong Kong, and Singapore and participate in the multinational EU-funded research programs SVDs@target and RECOGNISED. In 2016 I was appointed Fellow of the Royal College of Physicians Edinburgh and in 2015 I received the senior investigator award of the European Stroke Organisation (ESO) in recognition of my work.
Research Interests
Papers共 658 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
INTERNATIONAL JOURNAL OF STROKEno. 1 (2024): 7-15
Marvin Petersen,Mirthe Coenen,Charles DeCarli,Alberto De Luca, Ewoud van der Lelij, Alzheimer’s Disease Neuroimaging Initiative,Frederik Barkhof,Thomas Benke,Christopher P L H Chen,Peter Dal-Bianco,Anna Dewenter,Marco Duering,
medRxiv : the preprint server for health sciences (2024)
CLINICAL CARDIOLOGYno. 1 (2024): e24200-e24200
Geert Jan Biessels, G. J. Biessels
CEREBRAL CIRCULATION-COGNITION AND BEHAVIOR (2024): 100219-100219
Mirthe Coenen, Floor As de Kort,Nick A Weaver,Hugo J Kuijf,Hugo P Aben,Hee-Joon Bae,Régis Bordet, Christopher Plh Chen,Anna Dewenter, Thomas Doeven,Thibaut Dondaine,Marco Duering,
Cerebral Circulation - Cognition and Behavior (2024): 100113
Olivier Godefroy,Ardalan Aarabi,Yannick Béjot,Geert Jan Biessels, Bertrand Glize,Vincent Ct Mok,Michel Thiebaut de Schotten, Igor Sibon,Hugues Chabriat, Martine Roussel
European stroke journalpp.23969873241271651-23969873241271651, (2024)
Load More
Author Statistics
#Papers: 660
#Citation: 35423
H-Index: 93
G-Index: 177
Sociability: 8
Diversity: 4
Activity: 118
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn