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个人简介
Giulio Cossu (GC) is recognized for his pioneering work on skeletal myogenesis and for the first cell therapy trial with stem cells for muscular dystrophy.
He originally showed that neural tube (Vivarelli and Cossu, Dev. Biol. 1986) and, subsequently, dorsal ectoderm (Cossu et al., Development 1996) activate, through different Wnts, distinct myogenic programs in epaxial and hypaxial somitic progenitors, a notion now in developmental biology textbooks. He also pioneered studies on myogenic cell heterogeneity (Cossu and Molinaro, Curr. Topics Dev. Biol. 1987) by showing intrinsic differences among embryonic, foetal and adult myogenic progenitors (Biressi et al. Dev. Biol. 2007) whose molecular basis he recently elucidated (Messina et al. Cell 2010): these studies outlined an unforeseen parallelism with the hematopoietic system, supporting the idea that at least some tissues of developing mammals are built in subsequent stages by different families of progenitors.
研究兴趣
论文共 230 篇作者统计合作学者相似作者
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Simon Cauchemez,Giulio Cossu, Giulio Cossu, Giulio Cossu,Nathalie Delzenne, Eran Elinav, Eran Elinav, Didier Fassin,Alain Fischer,Alain Fischer,Alain Fischer,Alain Fischer,
Frontiers in Science (2024)
Francesco Galli,Laricia Bragg,Maira Rossi, Daisy Proietti,Laura Perani, Marco Bagicaluppi,Rossana Tonlorenzi, Tendai Sibanda,Miriam Caffarini, Avraneel Talapatra,Sabrina Santoleri,Mirella Meregalli,
EMBO molecular medicineno. 4 (2024): 927-944
EMBO Reportsno. 2 (2023)
Frontiers in immunology (2023): 1186224
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