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个人简介
After completing an undergraduate degree and M.Sc. (Biochemistry) at the University of Toronto, I moved to Vancouver to pursue a Ph.D. (Biochemistry and Molecular Biology). My work focused on identifying novel substrates for a class of proteases (MMPs) that contribute to cancer metastasis. I discovered that inflammatory chemokines were a new family of substrates for this enzyme family. After completing my Ph.D. I moved to England for my PDF at the MRC-Laboratory of Molecular Biology in Cambridge. I continued my work of proteolysis, but this time working with a new family of proteases, called Rhomboids. There I revealed their important activity within mitochondria. I started my lab ‘back home’ in 2005, and since, my research interests have focused on mitochondrial quality control, and how dysregulation leads to human disease. My lab currently balances basic science projects with translational studies and small molecule screening to develop novel therapeutics in neurodegenerative disease.
研究兴趣
论文共 40 篇作者统计合作学者相似作者
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Autophagyno. 4 (2023): 935-937
STAR PROTOCOLSno. 4 (2023): 102745-102745
Peter John Hawrysh,Jinghua Gao,Stephanie Tan, Amy Oh,Justin Nodwell,Thomas A. Tompkins,G. Angus McQuibban
Autophagyno. 7 (2023): 2094-2110
Sudeshna Nag,Kaitlin Szederkenyi, Olena Gorbenko, Hannah Tyrrell,Christopher M Yip,G Angus McQuibban
Cell reportsno. 8 (2023): 112895-112895
Natalia Moskal,Naomi Visanji, Olena Gorbenko,Vijay Narasimhan,Jess Nash,Peter N. Lewis,Angus McQuibban
SSRN Electronic Journal (2021)
Victoria Riccio, Nicholas Demers,Rong Hua,Miluska Vissa, Derrick T Cheng,Amy Wong Strilchuk,Yuqing Wang,G Angus McQuibban,Peter Kijun Kim
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