基本信息
views: 23
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
The Nakamura group focuses on the regulation of the cellular actin cytoskeleton and in particular on the molecular mechanisms of chemical and mechanical signal transduction (mechanotransduction), a conversion of mechanical forces into cellular biochemical signals. Mechanotransduction is essential for many physiological processes in diverse organisms during development and maintenance of all tissues. Defects in mechanotransduction, often caused by mutations or deregulation of proteins that disturb cellular or extracellular mechanics, are implicated in the development of various diseases, ranging from muscular dystrophies and hypertension-induced vascular and cardiac hypertrophy to cancer progression and metastasis. Despite its importance, little is known about the underlying mechanisms of mechanotransduction. The group uses a wide range of techniques including proteomics, microscopy, molecular biology, and cell biology, and appreciate collaboration with expertises in structural biology, mechanical engineering, single molecular analysis, computer simulation, and drug design.
Research Interests
Papers共 107 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCESno. 4 (2024): 2135
BIOCHEMICAL JOURNALno. 20 (2023): 1659-1674
The International journal of developmental biologyno. 2 (2023): 27-37
CYTOSKELETONno. 9-10 (2023): 382-392
Cytoskeletonno. 9-10 (2023): 382-392
Journal of cell scienceno. 6 (2023)
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn