基本信息
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Career Trajectory
Bio
Francesca Simorini received her Pharmacy degree from University of Pisa in 1989. She
remained at Pisa University- Department of Medicinal Chemistry - now "Department of Farmacy" where worked from
1991 to 2003 as a technician and since 2004 as an assistant professor. Her research was
directed towards the design and synthesis of heterocyclic systems potentially active in
various medicinal chemistry fields, such as aldose reductase inhibitors (“ARIs”), central
benzodiazepine receptor (“CBR”) ligands, peripheral benzodiazepine receptor
(“TSPO”) ligands. Moreover, she was involved in the synthesis of polyheterocyclic
molecules showing cytotoxic activity mainly attributable to an intercalative mode of
binding to DNA and in the synthesis of adenosine deaminase inhibitors (ADA), A3
adenosine receptor selective antagonists, Tyrosine Kinase inhibitors and Carbonic
Anhydrase inhibitors.
Research Interests
Papers共 61 篇Author StatisticsCo-AuthorSimilar Experts
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European journal of medicinal chemistry (2019): 46-58
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