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The overarching research objective of the Lund laboratory is to identify the key players that suppress or exacerbate mucosal inflammatory responses with the long-term goal of developing therapeutics to treat immunopathology associated with chronic infectious, allergic and autoimmune disease. One of the lab’s major projects is to characterize the roles that cytokine-producing “effector” B cells play in modulating inflammation and T cell-mediated immune responses to pathogens, autoantigens and allergens. In a second project, the lab evaluates how inflammatory signals regulate the balance between the development of the antibody-producing long-lived plasma cells and the memory B cell compartment within lymphoid tissues. The lab also studies how these cells are maintained long-term at inflammatory sites. Finally, the lab examines how oxidative stress induced by reactive oxygen species impacts inflammation, immune responses and cellular metabolism. In particular, the lab is experimentally modulating the NAD metabolome of immune cell in order to alter the responsiveness of these cells to oxidative stress.
Research Interests
Papers共 230 篇Author StatisticsCo-AuthorSimilar Experts
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Liliia Ibneeva,Sumeet Pal Singh,Anupam Sinha,Sema Elif Eski,Rebekka Wehner,Luise Rupp, Iryna Kovtun, Juan Alberto Pérez-Valencia,Alexander Gerbaulet,Susanne Reinhardt,Manja Wobus,Malte von Bonin,
Madeleine F. Jennewein,Michael D. Schultz,Samuel Beaver,Peter Battisti,Julie Bakken,Derek Hanson, Jobaida Akther,Raodoh Mohamath,Jasneet Singh, Noah Cross,Sierra Reed, Davies Kalange,
biorxiv(2023)
J T Killian,R G King,J L Kizziah, C F Fucile, R Diaz-Avalos,S Qiu, A Silva-Sanchez, B J Mousseau, K J Macon, A R Callahan, G Yang,M E Hossain,
bioRxiv : the preprint server for biology (2023)
Susan Bal,Esther Zumaquero,Gayathri Ravi,Kelly Godby,Smith Giri, Ashley Denslow, Joaquin Bauta Perez,Fen Zhou, Suki Chen, Megan Padilla,Amna Siddiqui,Clare Ubersax,
BLOOD (2023): 4685
Eddie-Williams Owiredu,John T. Killian,Rodney G. King, Jobaida Akther,Betty Mousseau,Esther Zumaquero,Fen Zhou, Suki Chen,Anoma Nellore,Alexander Rosenberg,Frances E. Lund
JOURNAL OF IMMUNOLOGYno. 1 (2023)
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AMERICAN JOURNAL OF TRANSPLANTATIONno. 1 (2023): S53-S53
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AMERICAN JOURNAL OF TRANSPLANTATIONno. 6 (2023): S369-S369
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Journal of Immunologyno. 1 (2023): 59.06-59.06
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