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个人简介
Back in belgium, he established his own laboratory progressively shifting the focus of his research from cardiovascular diseases to oncology. Cross-fertilization between these fields was instrumental in the identification by his lab of caveolae as unique signaling platforms involved in the regulation of endothelial NO synthase activity, angiogenesis and lipoprotein metabolism. This mixed expertise was also key to demonstrate the potential of a variety of vasomodulatory compounds to improve the efficacy of chemo- and radiotherapy.
Among the most recent discoveries of O. Feron's research group are the association between cycling hypoxia and tumor progression, the role of lactate as a key actor of tumor metabolic symbiosis, the metabolic shift from glucose toward glutamine and fatty acids in response to tumor microenvironment acidosis, and the link between polyunsaturated fatty acids, lipid droplets and ferroptosis.
Olivier Feron has obtained several awards including the prix Galien en 2000, the prix Eugène De Somer in 2008, the prix Lambertine Lacroix in 2010, the prix Pfizer in 2011, the prix Tytgat in 2017 and the prix Allard-Janssen in 2021. He is also editor-in-chief of the Journal Frontiers in Pharmacology of Anti-Cancer Drugs and member of the Royal Academy of Medicine since 2009.
研究兴趣
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Molecular Metabolism (2024): 101930-101930
Léo Aubert,Estelle Bastien, Ophélie Renoult,Céline Guilbaud, Kübra Özkan,Davide Brusa,Caroline Bouzin,Elena Richiardone,Corentin Richard,Romain Boidot, Daniel Léonard,Cyril Corbet,
EMBO Reportsno. 3 (2024): 1469-1489
Frontiers in pharmacology (2024): 1422847-1422847
Géraldine Cuvelier, Perrine Vermonden, Justine Rousseau,Olivier Féron,René Rezsöhazy,Yvan Larondelle
Frontiers in Cell Death (2023)
openalex(2023)
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