Feng Ren - Insilico Medicine Shanghai Ltd

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论文共 19 篇作者统计合作学者相似作者

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Abstract 412: Discovery and preclinical characterization of ISM9342A, a novel, potent, and orally bioavailable WRN inhibitor that suppresses MSI-H tumor growth

Pei Zhao, Wei Zhu,Xiaoyu Ding, Jianfei Wan, Xiaojing Chen, Man Zhang,Xiao Ding,Supriya Bavadekar,Sujata Rao,Feng Ren,Alex Zhavoronkov

Cancer Researchno. 6_Supplement (2024): 412-412

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Synthesis and structure-activity optimization of azepane-containing derivatives as PTPN2/PTPN1 inhibitors

Jiamin Zheng,Zhisen Zhang,Xiaoyu Ding,Deheng Sun,Lihua Min, Feng Wang,Sujing Shi,Xin Cai,Man Zhang,Alex Aliper,Feng Ren,Xiao Ding,

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2024): 116390-116390

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Abstract 1656: ISM6331, a novel and potent pan-TEAD inhibitor, exhibits strong anti-tumor activity in preclinical models of Hippo pathway-dysregulated cancers

Qi Li, Jainfei Wan, Jinxin Liu, Jing Shang, Jiaojiao Yu, Wei Zhu, Celia X.-J. Chen,Junwen Qiao, Ling Wang, Man Zhang,Xiao Ding,Supriya Bavadekar,

Cancer Researchno. 6_Supplement (2024): 1656-1656

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Abstract 5727: ISM9682A, a novel and potent KIF18A inhibitor, shows robust antitumor effects against chromosomally unstable cancers

Jie Zhang, Feng Gao, Wei Zhu,Chenxi Xu,Xiaoyu Ding, Jing Shang,Junwen Qiao, Shan Chen,Xin Cai,Xiao Ding,Supriya Bavadekar,Sujata Rao,

Cancer Researchno. 6_Supplement (2024): 5727-5727

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Abstract PO2-05-08: ISM5043, a novel, selective KAT6 inhibitor for the treatment of advanced and refractory ER+ breast cancer

Xin Cai, Xin Cheng,Luoheng Qin, Man Zhang,Junwen Qiao,Supriya Bavadekar,Sujata Rao,Feng Ren

Cancer Researchno. 9_Supplement (2024): PO2-05

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Discovery of a Novel and Potent Cyclin-Dependent Kinase 8/19 (CDK8/19) Inhibitor for the Treatment of Cancer

Jianyu Xu,Hongyun Qi, Zhen Wang,Ling Wang, Barbara Steurer,Xin Cai, Jinxin Liu,Alex Aliper, Man Zhang,Feng Ren,Alex Zhavoronkov,Xiao Ding

Journal of Medicinal Chemistryno. 10 (2024): 8161-8171

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Abstract 3967: ISM9182A, a novel HPK1 inhibitor, exhibits immune modulatory activity and robust monotherapy anti-tumor effects in preclinical studies

Celia X.-J. Chen, Congying Pu, Jingjing Peng,Xiaoyu Ding,Hongfu Lu,Xiao Ding, Man Zhang,Supriya Bavadekar,Sujata Rao,Feng Ren,Alex Zhavoronkov

Cancer Researchno. 6_Supplement (2024): 3967-3967

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Abstract 5582: Discovery and preclinical characterization of ISM8001, a covalent and selective FGFR2/FGFR3 dual inhibitor with strong monotherapy anti-tumor activity against advanced solid tumors

Yihong Zhang, Yazhou Wang,Xin Cai, Jinxin Liu, Hui Cui,Junwen Qiao, Xiaoxia Lin,Xiao Ding,Supriya Bavadekar,Sujata Rao, Man Zhang,Feng Ren,

Cancer Researchno. 6_Supplement (2024): 5582-5582

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Quantum Computing-Enhanced Algorithm Unveils Novel Inhibitors for KRAS

Mohammad Ghazi Vakili,Christoph Gorgulla,AkshatKumar Nigam,Dmitry Bezrukov, Daniel Varoli,Alex Aliper, Daniil Polykovsky,Krishna M. Padmanabha Das,Jamie Snider,Anna Lyakisheva, Ardalan Hosseini Mansob,Zhong Yao,

CoRR (2024)

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Abstract 502: ISM3091, a Novel Selective USP1 Inhibitor As a Targeted Anticancer Therapy

Yangguang Li,Jianping Wu, Jinxin Liu,Luoheng Qin,Xin Cai,Junwen Qiao, Ling Wang,Sujata Rao,Feng Ren,Alex Zhavoronkov

Cancer researchno. 7_Supplement (2023): 502-502

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