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Research Interests
Understanding, monitoring, and modulating T cell function. T cells play pivotal roles in human adaptive immune response and have been implicated in a wide array of diseases, such as autoimmunity, allergy, cancer, and infectious diseases, as well as vaccine design and evaluation. The research goal is to harness the immunological power of T cells to fight cancer and infections and to control their undesired behaviors associated with autoimmunity and allergy. To achieve this goal, my group focuses on developing molecular engineering tools, such as protein-based nanoparticles, multiplexed T cell functional marker biosensor, and synthetic gene/antigen delivery viral particles.
Producing sustainable biofuels using engineered microbes. My group is also interested in engineering microbes that are capable of converting lignocellulosic biomass to alternative biofuels, such as ethanol. The focus here is biomass-degrading enzyme activity engineering with the aim of identifying protein mutants that could break down biomass efficiently. Meanwhile, microbial metabolic engineering is employed with the aim of improving the biofuel yield and titer.
Understanding, monitoring, and modulating T cell function. T cells play pivotal roles in human adaptive immune response and have been implicated in a wide array of diseases, such as autoimmunity, allergy, cancer, and infectious diseases, as well as vaccine design and evaluation. The research goal is to harness the immunological power of T cells to fight cancer and infections and to control their undesired behaviors associated with autoimmunity and allergy. To achieve this goal, my group focuses on developing molecular engineering tools, such as protein-based nanoparticles, multiplexed T cell functional marker biosensor, and synthetic gene/antigen delivery viral particles.
Producing sustainable biofuels using engineered microbes. My group is also interested in engineering microbes that are capable of converting lignocellulosic biomass to alternative biofuels, such as ethanol. The focus here is biomass-degrading enzyme activity engineering with the aim of identifying protein mutants that could break down biomass efficiently. Meanwhile, microbial metabolic engineering is employed with the aim of improving the biofuel yield and titer.
Research Interests
Papers共 47 篇Author StatisticsCo-AuthorSimilar Experts
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Brett D Hill,Andrew J Zak, Sanjeev Raja,Luke F Bugada,Syed M Rizvi, Saiful B Roslan, Hong Nhi Nguyen,Judy Chen, Hui Jiang, Akira Ono,Daniel R Goldstein,Fei Wen
JCI insightno. 12 (2024)
Chengyi Li,Ryan Clauson,Luke F. Bugada,Fang Ke,Bing He, Zhixin Yu,Hongwei Chen, Binyamin Jacobovitz,Hongxiang Hu, Polina Chuikov,Brett Dallas Hill,Syed M. Rizvi,
Chengyi Li,Shuai Mao, Hongyi Zhao, Djibo Mahamadou, Zhongwei Liu, Hanning Wen,Miao He,Meilin Wang,Jinsong Tao,Bo Wen,Trang Hoang, Binyamin Jacobovitz,
Cancer Researchno. 6_Supplement (2024): 6534-6534
Bioresource Technology (2024): 130377-130377
ACS Synthetic Biologyno. 4 (2024): 1225-1236
Heliyonno. 8 (2023): e18848-e18848
World journal of gastrointestinal oncologyno. 7 (2023): 1215-1226
International Journal of Molecular Sciencesno. 14622 (2023): 14622-14622
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Author Statistics
#Papers: 48
#Citation: 1940
H-Index: 18
G-Index: 44
Sociability: 5
Diversity: 0
Activity: 1
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