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个人简介
Professor Fazal Subhan
Designation: Professor
Email: fazal_subhan@upesh.edu.pk
Phone: Off: 091-921675
Address:
Department of Pharmacy, University of Peshawar, Khyber Pakhtunkhwa, Pakistan
Qualification:
Ph.D (UK)
Specialization:
Pharmacy (Pharmacology)
Brief Statement of Research Interests:
Research activities in this group are focused on testing compounds from both synthetic and natural origin for its utility in pain, inflammation, pyrexia depression, anxiety, dependence, tolerance, and vomiting.
Research is in progress in the area of diabetic neuropathy where the pathological condition is induced in rat model with streptozotocin. The pain models of allodynia and vulvodynia associated with diabetes are developed and the compounds of interest are tested for effectiveness in these pain conditions with the help of von Frey hairs. Research is also in progress both at the preclinical and clinical levels for testing newly developed antipsychotic formulations in comparison to conventional formulations for its safety and therapeutic efficacy. Beside, the group is working on natural products against chemotherapeutic drugs induced vomiting and opioid withdrawal syndrome.
Biochemical and neurotransmitters studies are conducted for correlating behavioral findings and elucidation of mechanism of action of compounds of interest.
Facilities:
• Animal house with the breeding and keeping facilities of rats, mice, pigeons, rabbits and guinea pigs.
• Behavioral laboratory equipped with computer assisted video recording facility for experiments on live animals such as analgesia, anti-inflammatory, antipyretic, anti-emetic, locomotor, anxiolytic and antidepressant activities.
• Toxicological laboratory with facility of tissue embedding and staining, microtome for tissue slicing, microscope attached with camera and computer for examining of tissue slides.
• Applied Pharmacology laboratory with the facilities of; -80 ºC fridges, tissue homogenizer for processing tissue, temperature controlled centrifuge, HPLC with UV and ECD detectors. ESA, Electrochemical Detector is equipped with high sensitivity analytical cell and guard cell for measurement of minute quantities of neurotransmitters and other biomarkers in the biological fluids including the brain areas of interest.
• Universal organ bath and Oscillograph and chart recorders for isolated tissue experiments.
研究兴趣
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Neurology Asiano. 1 (2024): 157-165
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2024): 150217-150217
Shehla Akbar,Fazal Subhan, Aroosha Akbar, Faiza Habib,Naila Shahbaz,Ashfaq Ahmad,Abdul Wadood,Saad Salman
Nutrientsno. 11 (2023): 2552-2552
International immunopharmacology (2022): 108674-108674
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