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个人简介
Dr. Fabrizio Mattei graduated from University “La Sapienza” in Rome and completed his specialization in biotechnologies and oncology at the same university. In 2000, he became a fellow at the Edward Jenner Institute for Vaccine Research in David Tough's laboratory (Newbury, U.K.), where he acquired experience in the field of dendritic cell immunology. He is currently a Senior Researcher, Group Leader and Principal Investigator at the Istituto Superiore di Sanità (Rome, Italy), where he has focused on the molecular interactions between dendritic cells and type I Interferons signalling. His current research is aimed at understanding the role of Interferons signalling in the interface between tumor and immune system in both mouse and human models. Furthermore, he is also conducting research aimed at investigating on crosstalk between immune system and cancer by Cell-on-Chip devices. In a recent collaboration with Prof. Guido Kroemer, Dr. Mattei and his staff contributed to demonstrate the key role of the Formyl Peptide Receptor 1 in chemotherapy-induced anticancer immunity in breast and colon tumors by exploiting ad hoc fabricated microfluidic chips to study the interactions between these tumor cells and immune cells from patients with normal, mutated and heterozygous form of this receptor. Regarding its editorial activity, Dr. Mattei is currently member of the Editorial Board of various distinguished international scientific journals, including PLoS ONE, Nature Scientific Reports, OncoImmunology and Journal of Experimental & Clinical Cancer Research. In addition, Dr. Mattei conducts extensive reviewer activity for various PubMed-indexed journals, such as Nanoscale, Journal of Pathology, The Journal of Immunology, Molecular Cancer Research and Cancer Letters. Dr. Mattei also acts as project evaluator for some international funding agencies.
研究兴趣
论文共 86 篇作者统计合作学者相似作者
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Adriana Rosa Gambardella, Caterina Antonucci,Cristiana Zanetti, Francesco Noto,Sara Andreone,Davide Vacca, Valentina Pellerito, Chiara Sicignano, Giuseppe Parrottino,Valentina Tirelli,Antonella Tinari,Mario Falchi,
Journal of experimental & clinical cancer research : CRno. 1 (2024): 209-209
Valeria Cancila,Gaia Morello,Giorgio Bertolazzi, Allison Si-Yu Chan,Giulia Bastianello, Daniel Paysan,Patrick William Jaynes,Giovanna Schiavoni,Fabrizio Mattei,Silvia Piconese,Maria V Revuelta, Francesco Noto,
Research square (2024)
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