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Bio
Chiti provided contributions in the field of misfolding and aggregation, particularly in the field of amyloid.He rationalized how amino acid mutations induce protein aggregation and edited an equation to predict the effect of mutations on the aggregation of an unfolded protein,which led to a search by many investigators of algorithms with predictive power on essential aspects of protein aggregation. He also correlated the toxicities of abnormal protein oligomers with specific structural properties of them. His 2006 review with Chris Dobson on protein misfolding, amyloid formation and human disease,later updated as a new report, is a reference paper in the field of amyloid and received, as of October 2019, more than four thousands citations in scientific publications.
Research Interests
Papers共 193 篇Author StatisticsCo-AuthorSimilar Experts
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Translational Neurodegenerationno. 1 (2024): 1-5
Journal of chemical theory and computation (2024)
ALZHEIMERS RESEARCH & THERAPYno. 1 (2024)
TRANSLATIONAL NEURODEGENERATIONno. 1 (2024): 14-14
JOURNAL OF THE AMERICAN CHEMICAL SOCIETYno. 15 (2024): 10537-10549
Journal of the American Chemical Societyno. 15 (2024): 10537-10549
Alzheimer's Research & Therapyno. 1 (2024): 1-19
Molecular Neurodegenerationno. 1 (2024): 1-32
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